DHA

Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.

References related to abnormalities published in Am. J. Clin. Nutr.

PMID	Journal	Published Date	Author	Title
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12399272	Am. J. Clin. Nutr.	2002	Woodman RJ et al.	Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension.
12600840	Am. J. Clin. Nutr.	2003	Terry PD et al.	Intakes of fish and marine fatty acids and the risks of cancers of the breast and prostate and of other hormone-related cancers: a review of the epidemiologic evidence.
12499346	Am. J. Clin. Nutr.	2003	Francois CA et al.	Supplementing lactating women with flaxseed oil does not increase docosahexaenoic acid in their milk.
10617987	Am. J. Clin. Nutr.	2000	Makrides M and Gibson RA	Long-chain polyunsaturated fatty acid requirements during pregnancy and lactation.
10799369	Am. J. Clin. Nutr.	2000	Mori TA et al.	Purified eicosapentaenoic and docosahexaenoic acids have differential effects on serum lipids and lipoproteins, LDL particle size, glucose, and insulin in mildly hyperlipidemic men.
10966891	Am. J. Clin. Nutr.	2000	Wander RC and Du SH	Oxidation of plasma proteins is not increased after supplementation with eicosapentaenoic and docosahexaenoic acids.
15113713	Am. J. Clin. Nutr.	2004	Stark KD and Holub BJ	Differential eicosapentaenoic acid elevations and altered cardiovascular disease risk factor responses after supplementation with docosahexaenoic acid in postmenopausal women receiving and not receiving hormone replacement therapy.
14684413	Am. J. Clin. Nutr.	2004	Nilsen DW and Harris WS	n-3 Fatty acids and cardiovascular disease.
14668274	Am. J. Clin. Nutr.	2003	Stene LC and Joner G	Use of cod liver oil during the first year of life is associated with lower risk of childhood-onset type 1 diabetes: a large, population-based, case-control study.
19176727	Am. J. Clin. Nutr.	2009	O'Brien DM et al.	Red blood cell delta15N: a novel biomarker of dietary eicosapentaenoic acid and docosahexaenoic acid intake.
19056552	Am. J. Clin. Nutr.	2009	di Giuseppe R et al.	Alcohol consumption and n-3 polyunsaturated fatty acids in healthy men and women from 3 European populations.
19515734	Am. J. Clin. Nutr.	2009	Bouwens M et al.	Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells.
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20335550	Am. J. Clin. Nutr.	2010	Yee LD et al.	Omega-3 fatty acid supplements in women at high risk of breast cancer have dose-dependent effects on breast adipose tissue fatty acid composition.
20219958	Am. J. Clin. Nutr.	2010	Heine-Bröring RC et al.	Intake of fish and marine n-3 fatty acids in relation to coronary calcification: the Rotterdam Study.
19864410	Am. J. Clin. Nutr.	2009	Nash SH et al.	Relation between stable isotope ratios in human red blood cells and hair: implications for using the nitrogen isotope ratio of hair as a biomarker of eicosapentaenoic acid and docosahexaenoic acid.
20071644	Am. J. Clin. Nutr.	2010	Stirban A et al.	Effects of n-3 fatty acids on macro- and microvascular function in subjects with type 2 diabetes mellitus.
20089728	Am. J. Clin. Nutr.	2010	Makhoul Z et al.	Associations of very high intakes of eicosapentaenoic and docosahexaenoic acids with biomarkers of chronic disease risk among Yup'ik Eskimos.
21865334	Am. J. Clin. Nutr.	2011	Sanders TA et al.	Effect of low doses of long-chain n-3 PUFAs on endothelial function and arterial stiffness: a randomized controlled trial.
21849598	Am. J. Clin. Nutr.	2011	Miles EA et al.	The Salmon in Pregnancy Study: study design, subject characteristics, maternal fish and marine n-3 fatty acid intake, and marine n-3 fatty acid status in maternal and umbilical cord blood.
17490956	Am. J. Clin. Nutr.	2007	Metcalf RG et al.	Effects of fish-oil supplementation on myocardial fatty acids in humans.
17490978	Am. J. Clin. Nutr.	2007	Krauss-Etschmann S et al.	Effects of fish-oil and folate supplementation of pregnant women on maternal and fetal plasma concentrations of docosahexaenoic acid and eicosapentaenoic acid: a European randomized multicenter trial.
17413088	Am. J. Clin. Nutr.	2007	Connor WE and Connor SL	The importance of fish and docosahexaenoic acid in Alzheimer disease.
17413117	Am. J. Clin. Nutr.	2007	van Gelder BM et al.	Fish consumption, n-3 fatty acids, and subsequent 5-y cognitive decline in elderly men: the Zutphen Elderly Study.
18065578	Am. J. Clin. Nutr.	2007	Harris WS et al.	Comparison of the effects of fish and fish-oil capsules on the n 3 fatty acid content of blood cells and plasma phospholipids.
15531662	Am. J. Clin. Nutr.	2004	Giltay EJ et al.	Docosahexaenoic acid concentrations are higher in women than in men because of estrogenic effects.
17158409	Am. J. Clin. Nutr.	2006	Philibert A et al.	Fish intake and serum fatty acid profiles from freshwater fish.
17158437	Am. J. Clin. Nutr.	2006	Kamphuis MH et al.	Depression and cardiovascular mortality: a role for n-3 fatty acids?
17158440	Am. J. Clin. Nutr.	2006	Demonty I et al.	Fish-oil esters of plant sterols improve the lipid profile of dyslipidemic subjects more than do fish-oil or sunflower oil esters of plant sterols.
16825699	Am. J. Clin. Nutr.	2006	Niu K et al.	Dietary long-chain n-3 fatty acids of marine origin and serum C-reactive protein concentrations are associated in a population with a diet rich in marine products.
18469236	Am. J. Clin. Nutr.	2008	Vaisman N et al.	Correlation between changes in blood fatty acid composition and visual sustained attention performance in children with inattention: effect of dietary n-3 fatty acids containing phospholipids.
18469279	Am. J. Clin. Nutr.	2008	Johnson EJ et al.	The influence of supplemental lutein and docosahexaenoic acid on serum, lipoproteins, and macular pigmentation.
18689376	Am. J. Clin. Nutr.	2008	Augood C et al.	Oily fish consumption, dietary docosahexaenoic acid and eicosapentaenoic acid intakes, and associations with neovascular age-related macular degeneration.
18779287	Am. J. Clin. Nutr.	2008	van de Rest O et al.	Effect of fish-oil supplementation on mental well-being in older subjects: a randomized, double-blind, placebo-controlled trial.
18779289	Am. J. Clin. Nutr.	2008	Lindberg M et al.	Long-chain n-3 fatty acids and mortality in elderly patients.
23446897	Am. J. Clin. Nutr.	2013	West AA et al.	Choline intake influences phosphatidylcholine DHA enrichment in nonpregnant women but not in pregnant women in the third trimester.