phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

References related to genes published in Am. J. Clin. Nutr.


PMIDJournalPublished DateAuthorTitle
11722960Am. J. Clin. Nutr.2001Booth SL et al.Effects of a hydrogenated form of vitamin K on bone formation and resorption.
12399278Am. J. Clin. Nutr.2002Binkley NC et al.A high phylloquinone intake is required to achieve maximal osteocalcin gamma-carboxylation.
11101481Am. J. Clin. Nutr.2000Binkley NC et al.Vitamin K supplementation reduces serum concentrations of under-gamma-carboxylated osteocalcin in healthy young and elderly adults.
20881072Am. J. Clin. Nutr.2010Kumar R et al.Effect of phylloquinone supplementation on glucose homeostasis in humans.
17684225Am. J. Clin. Nutr.2007Troy LM et al.Dihydrophylloquinone intake is associated with low bone mineral density in men and women.
18400723Am. J. Clin. Nutr.2008Nimptsch K et al.Dietary intake of vitamin K and risk of prostate cancer in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Heidelberg).
23034962Am. J. Clin. Nutr.2012Ibarrola-Jurado N et al.Dietary phylloquinone intake and risk of type 2 diabetes in elderly subjects at high risk of cardiovascular disease.