Cholic acid
Cholic acid is a lipid of Sterol Lipids (ST) class. Cholic acid is associated with abnormalities such as Cholestasis, Intrahepatic Cholestasis, Atherosclerosis, Diabetes and cholesterol gallstones. The involved functions are known as Homeostasis, Enterohepatic Circulation, Proliferation (morphologic abnormality), Process and Cell Proliferation. Cholic acid often locates in Hepatic, Cytoplasmic matrix, Membrane, Protoplasm and Tissue membrane. The associated genes with Cholic acid are CYP27A1 gene, ABCB11 gene, NR5A2 gene, SLC10A2 gene and SLC10A1 gene. The related lipids are ursocholic acid, Steroids, Cholestenes, Cholestanes and cholanic acid.
References related to lipids published in Am. J. Physiol. Gastrointest. Liver Physiol.
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 11751172 | Am. J. Physiol. Gastrointest. Liver Physiol. | 2002 | Zollner G et al. | Induction of short heterodimer partner 1 precedes downregulation of Ntcp in bile duct-ligated mice. |
| 14684380 | Am. J. Physiol. Gastrointest. Liver Physiol. | 2004 | Xu G et al. | Dietary cholesterol stimulates CYP7A1 in rats because farnesoid X receptor is not activated. |
| 26744468 | Am. J. Physiol. Gastrointest. Liver Physiol. | 2016 | Kong B et al. | Mice with hepatocyte-specific FXR deficiency are resistant to spontaneous but susceptible to cholic acid-induced hepatocarcinogenesis. |