Lycopene

Lycopene is a lipid of Prenol Lipids (PR) class. Lycopene is associated with abnormalities such as Consumption-archaic term for TB, Chronic disease, Dehydration, furuncle and Cardiovascular Diseases. The involved functions are known as Cell Differentiation process, Signal Transduction, Biochemical Pathway, Mutation and IGF-1 Signaling Pathway. Lycopene often locates in Body tissue, Hepatic, Blood, Adipose tissue and Structure of parenchyma of lung. The associated genes with Lycopene are EPB41L2 gene, VEGFB gene, P4HTM gene, FATE1 gene and SLC33A1 gene. The related lipids are Micelles, Liposomes, Total cholesterol, Steroids and apo-10'-lycopenoic acid. The related experimental models are Mouse Model, Knock-out, Cancer Model, Transgenic Model and Xenograft Model.

References related to abnormalities published in Am. J. Clin. Nutr.


PMIDJournalPublished DateAuthorTitle
10197573Am. J. Clin. Nutr.1999Riso P et al.Does tomato consumption effectively increase the resistance of lymphocyte DNA to oxidative damage?
10500017Am. J. Clin. Nutr.1999Paetau I et al.Carotenoids in human buccal mucosa cells after 4 wk of supplementation with tomato juice or lycopene supplements.
12499332Am. J. Clin. Nutr.2003Rissanen TH et al.Serum lycopene concentrations and carotid atherosclerosis: the Kuopio Ischaemic Heart Disease Risk Factor Study.
14684396Am. J. Clin. Nutr.2004Sesso HD et al.Plasma lycopene, other carotenoids, and retinol and the risk of cardiovascular disease in women.
14668286Am. J. Clin. Nutr.2003Erhardt JG et al.Lycopene, beta-carotene, and colorectal adenomas.
21543537Am. J. Clin. Nutr.2011Ross AB et al.Lycopene bioavailability and metabolism in humans: an accelerator mass spectrometry study.
20392890Am. J. Clin. Nutr.2010Talvas J et al.Differential effects of lycopene consumed in tomato paste and lycopene in the form of a purified extract on target genes of cancer prostatic cells.
20685953Am. J. Clin. Nutr.2010Mayne ST et al.Noninvasive assessment of dermal carotenoids as a biomarker of fruit and vegetable intake.
17991659Am. J. Clin. Nutr.2007Vrieling A et al.Lycopene supplementation elevates circulating insulin-like growth factor binding protein-1 and -2 concentrations in persons at greater risk of colorectal cancer.
15883420Am. J. Clin. Nutr.2005Sesso HD et al.Plasma lycopene, other carotenoids, and retinol and the risk of cardiovascular disease in men.
16762935Am. J. Clin. Nutr.2006Voutilainen S et al.Carotenoids and cardiovascular health.
18779292Am. J. Clin. Nutr.2008Wang L et al.Associations of plasma carotenoids with risk factors and biomarkers related to cardiovascular disease in middle-aged and older women.
22492370Am. J. Clin. Nutr.2012Thies F et al.Effect of a tomato-rich diet on markers of cardiovascular disease risk in moderately overweight, disease-free, middle-aged adults: a randomized controlled trial.
22854412Am. J. Clin. Nutr.2012Wood LG et al.Manipulating antioxidant intake in asthma: a randomized controlled trial.
23053550Am. J. Clin. Nutr.2012Sharoni Y et al.The role of lycopene and its derivatives in the regulation of transcription systems: implications for cancer prevention.
23053559Am. J. Clin. Nutr.2012Wang XDLycopene metabolism and its biological significance.