Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

References related to abnormalities published in Antimicrob. Agents Chemother.


PMIDJournalPublished DateAuthorTitle
14506046Antimicrob. Agents Chemother.2003Collier CT et al.Effects of tylosin on bacterial mucolysis, Clostridium perfringens colonization, and intestinal barrier function in a chick model of necrotic enteritis.
14576111Antimicrob. Agents Chemother.2003Jost BH et al.Tylosin resistance in Arcanobacterium pyogenes is encoded by an erm X determinant.
17353243Antimicrob. Agents Chemother.2007Lin J et al.Effect of macrolide usage on emergence of erythromycin-resistant Campylobacter isolates in chickens.
14982756Antimicrob. Agents Chemother.2004Jost BH et al.A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.
22926570Antimicrob. Agents Chemother.2012Andersen NM et al.Inhibition of protein synthesis on the ribosome by tildipirosin compared with other veterinary macrolides.
21555771Antimicrob. Agents Chemother.2011Hidalgo Á et al.Trends towards lower antimicrobial susceptibility and characterization of acquired resistance among clinical isolates of Brachyspira hyodysenteriae in Spain.