erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

References related to genes published in Antimicrob. Agents Chemother.

PMID	Journal	Published Date	Author	Title
10428903	Antimicrob. Agents Chemother.	1999	Johnson MM et al.	Effect of carbon dioxide on testing of susceptibilities of respiratory tract pathogens to macrolide and azalide antimicrobial agents.
10428930	Antimicrob. Agents Chemother.	1999	Credito KL et al.	Activity of telithromycin (HMR 3647) against anaerobic bacteria compared to those of eight other agents by time-kill methodology.
10348746	Antimicrob. Agents Chemother.	1999	Champney WS and Tober CL	Molecular investigation of the postantibiotic effects of clarithromycin and erythromycin on Staphylococcus aureus cells.
11408246	Antimicrob. Agents Chemother.	2001	Nilius AM et al.	Comparative in vitro activity of ABT-773, a novel antibacterial ketolide.
12183262	Antimicrob. Agents Chemother.	2002	Ng LK et al.	Mutation in 23S rRNA associated with macrolide resistance in Neisseria gonorrhoeae.
12183270	Antimicrob. Agents Chemother.	2002	Prunier AL et al.	Clinical isolates of Staphylococcus aureus with ribosomal mutations conferring resistance to macrolides.
10722500	Antimicrob. Agents Chemother.	2000	Brophy DF et al.	Pharmacokinetic interaction between amprenavir and clarithromycin in healthy male volunteers.
10681362	Antimicrob. Agents Chemother.	2000	Poyart C et al.	Characterization of the Tn916-like transposon Tn3872 in a strain of abiotrophia defectiva (Streptococcus defectivus) causing sequential episodes of endocarditis in a child.
14693558	Antimicrob. Agents Chemother.	2004	Betriu C et al.	In vitro activities of tigecycline against erythromycin-resistant Streptococcus pyogenes and Streptococcus agalactiae: mechanisms of macrolide and tetracycline resistance.
21537028	Antimicrob. Agents Chemother.	2011	Loreto ES et al.	In vitro susceptibility of Pythium insidiosum to macrolides and tetracycline antibiotics.
19273669	Antimicrob. Agents Chemother.	2009	Beeton ML et al.	Concurrent titration and determination of antibiotic resistance in ureaplasma species with identification of novel point mutations in genes associated with resistance.
20606071	Antimicrob. Agents Chemother.	2010	Bohnert JA et al.	Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates.
20585125	Antimicrob. Agents Chemother.	2010	Chisholm SA et al.	High-level azithromycin resistance occurs in Neisseria gonorrhoeae as a result of a single point mutation in the 23S rRNA genes.
17908942	Antimicrob. Agents Chemother.	2007	Binet R and Maurelli AT	Frequency of development and associated physiological cost of azithromycin resistance in Chlamydia psittaci 6BC and C. trachomatis L2.
17606685	Antimicrob. Agents Chemother.	2007	Gibreel A et al.	Contribution of the CmeABC efflux pump to macrolide and tetracycline resistance in Campylobacter jejuni.
18212111	Antimicrob. Agents Chemother.	2008	Tsuda T et al.	Effect of 14-membered-ring macrolides on production of interleukin-8 mediated by protease-activated receptor 2 in human keratinocytes.
14982769	Antimicrob. Agents Chemother.	2004	Sugie M et al.	Possible involvement of the drug transporters P glycoprotein and multidrug resistance-associated protein Mrp2 in disposition of azithromycin.
16251306	Antimicrob. Agents Chemother.	2005	Wierzbowski AK et al.	Expression of the mef(E) gene encoding the macrolide efflux pump protein increases in Streptococcus pneumoniae with increasing resistance to macrolides.
15917536	Antimicrob. Agents Chemother.	2005	Bosnar M et al.	Cellular uptake and efflux of azithromycin, erythromycin, clarithromycin, telithromycin, and cethromycin.