Avermectin A1a

Avermectin A1a is a lipid of Polyketides (PK) class. Avermectin a1a is associated with abnormalities such as Ataxia with vitamin E deficiency, Strongyloidiasis, Congenital Transposition, Gigantism and Onchocerciasis. The involved functions are known as DNA Binding, Anabolism, Insertion Mutation, Process and physiological aspects. Avermectin a1a often locates in Chromosomes, Membrane, Clone, soluble and Tissue membrane. The associated genes with Avermectin A1a are Polypeptides, oxytocin, 1-desamino-(O-Et-Tyr)(2)-, Gene Feature, Genome and Gene Clusters. The related lipids are Propionate. The related experimental models are Mouse Model.

References related to genes published in Appl. Environ. Microbiol.


PMIDJournalPublished DateAuthorTitle
12571055Appl. Environ. Microbiol.2003Hwang YS et al.Cloning and analysis of a DNA fragment stimulating avermectin production in various Streptomyces avermitilis strains.
17483257Appl. Environ. Microbiol.2007Trefzer A et al.Biocatalytic conversion of avermectin to 4''-oxo-avermectin: improvement of cytochrome p450 monooxygenase specificity by directed evolution.
26002902Appl. Environ. Microbiol.2015Liu W et al.Increasing Avermectin Production in Streptomyces avermitilis by Manipulating the Expression of a Novel TetR-Family Regulator and Its Target Gene Product.