7alpha-Hydroxycholesterol
7alpha-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 7alpha-hydroxycholesterol is associated with abnormalities such as Atherosclerosis, Morphologically altered structure, Carotid Atherosclerosis, Myocardial Infarction and Cerebrovascular accident. The involved functions are known as Apoptosis, Cell Growth, Necrosis, Chromosome Condensation and Tissue Adhesions. 7alpha-hydroxycholesterol often locates in Arterial system, Endothelium, Cell Nucleus, Membrane and yolk. The associated genes with 7alpha-Hydroxycholesterol are acetyl-aspartyl-glutamyl-valyl-aspartal, BCL2 gene, OGFR gene, Genome and GAPDH gene. The related lipids are Hydroxycholesterols, 7-ketocholesterol, Ketocholesterols, 20-hydroxycholesterol and 25-hydroxycholesterol.
References related to abnormalities published in Arterioscler. Thromb. Vasc. Biol.
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 10323769 | Arterioscler. Thromb. Vasc. Biol. | 1999 | Lizard G et al. | Characterization and comparison of the mode of cell death, apoptosis versus necrosis, induced by 7beta-hydroxycholesterol and 7-ketocholesterol in the cells of the vascular wall. |
| 10195924 | Arterioscler. Thromb. Vasc. Biol. | 1999 | Ziedén B et al. | Increased plasma 7 beta-hydroxycholesterol concentrations in a population with a high risk for cardiovascular disease. |
| 12663372 | Arterioscler. Thromb. Vasc. Biol. | 2003 | Chang MY et al. | Lysophosphatidylcholine regulates synthesis of biglycan and the proteoglycan form of macrophage colony stimulating factor. |
| 11451740 | Arterioscler. Thromb. Vasc. Biol. | 2001 | Li W et al. | Apoptotic death of inflammatory cells in human atheroma. |