butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

References related to abnormalities published in Blood

PMID	Journal	Published Date	Author	Title
2473801	Blood	1989	Perrine SP et al.	Sodium butyrate enhances fetal globin gene expression in erythroid progenitors of patients with Hb SS and beta thalassemia.
8422469	Blood	1993	Blau CA et al.	Fetal hemoglobin induction with butyric acid: efficacy and toxicity.
10648397	Blood	2000	Smith RD et al.	Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells.
11071627	Blood	2000	Reich S et al.	Oral isobutyramide reduces transfusion requirements in some patients with homozygous beta-thalassemia.
11090069	Blood	2000	Maeda T et al.	Up-regulation of costimulatory/adhesion molecules by histone deacetylase inhibitors in acute myeloid leukemia cells.
10942396	Blood	2000	Koyama Y et al.	Histone deacetylase inhibitors suppress IL-2-mediated gene expression prior to induction of apoptosis.
10733512	Blood	2000	Witt O et al.	Butyrate-induced erythroid differentiation of human K562 leukemia cells involves inhibition of ERK and activation of p38 MAP kinase pathways.