butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

References related to functions published in Blood


PMIDJournalPublished DateAuthorTitle
2446679Blood1988Hutt-Taylor SR et al.Sodium butyrate and a T lymphocyte cell line-derived differentiation factor induce basophilic differentiation of the human promyelocytic leukemia cell line HL-60.
3015282Blood1986McCachren SS et al.Dibutyryl cyclic adenosine monophosphate reduces expression of c-myc during HL-60 differentiation.
3128344Blood1988Inhorn L et al.Restoration of adenylate cyclase responsiveness in murine myeloid leukemia permits inhibition of proliferation by hormone. Butyrate augments catalytic activity of adenylate cyclase.
3080038Blood1986Tandon NN et al.Synergistic effects of butyrate on platelet responses to arachidonate, A23187, PGE1, and forskolin.
6203577Blood1984Faille A et al.Differential expression of HLA-DR and HLA-DC/DS molecules in a patient with hairy cell leukemia: restoration of HLA-DC/DS expression by (12-0-tetradecanoyl phorbol-13-acetate), 5 azacytidine, and sodium butyrate.
7949149Blood1994Safaya S et al.Augmentation of gamma-globin gene promoter activity by carboxylic acids and components of the human beta-globin locus control region.
7579338Blood1995Rubio MA et al.Granulocyte-macrophage colony-stimulating factor, phorbol ester, and sodium butyrate induce the CD11c integrin gene promoter activity during myeloid cell differentiation.
9746790Blood1998Moulding DA et al.Mcl-1 expression in human neutrophils: regulation by cytokines and correlation with cell survival.
10648397Blood2000Smith RD et al.Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells.
11071627Blood2000Reich S et al.Oral isobutyramide reduces transfusion requirements in some patients with homozygous beta-thalassemia.
10942396Blood2000Koyama Y et al.Histone deacetylase inhibitors suppress IL-2-mediated gene expression prior to induction of apoptosis.
10733512Blood2000Witt O et al.Butyrate-induced erythroid differentiation of human K562 leukemia cells involves inhibition of ERK and activation of p38 MAP kinase pathways.