butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

References related to genes published in Blood


PMIDJournalPublished DateAuthorTitle
2446679Blood1988Hutt-Taylor SR et al.Sodium butyrate and a T lymphocyte cell line-derived differentiation factor induce basophilic differentiation of the human promyelocytic leukemia cell line HL-60.
2460154Blood1988Burns LJ et al.Butyrate induces selective transcriptional activation of a hypomethylated embryonic globin gene in adult erythroid cells.
6203577Blood1984Faille A et al.Differential expression of HLA-DR and HLA-DC/DS molecules in a patient with hairy cell leukemia: restoration of HLA-DC/DS expression by (12-0-tetradecanoyl phorbol-13-acetate), 5 azacytidine, and sodium butyrate.
7691251Blood1993Fibach E et al.Enhanced fetal hemoglobin production by phenylacetate and 4-phenylbutyrate in erythroid precursors derived from normal donors and patients with sickle cell anemia and beta-thalassemia.
8507862Blood1993Zon LI et al.Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription.
7949149Blood1994Safaya S et al.Augmentation of gamma-globin gene promoter activity by carboxylic acids and components of the human beta-globin locus control region.
9746790Blood1998Moulding DA et al.Mcl-1 expression in human neutrophils: regulation by cytokines and correlation with cell survival.
10648397Blood2000Smith RD et al.Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells.
10828043Blood2000Gabbianelli M et al.Hemoglobin switching in unicellular erythroid culture of sibling erythroid burst-forming units: kit ligand induces a dose-dependent fetal hemoglobin reactivation potentiated by sodium butyrate.
10942396Blood2000Koyama Y et al.Histone deacetylase inhibitors suppress IL-2-mediated gene expression prior to induction of apoptosis.
10733512Blood2000Witt O et al.Butyrate-induced erythroid differentiation of human K562 leukemia cells involves inhibition of ERK and activation of p38 MAP kinase pathways.