Cucurbitacin B

Cucurbitacin b is a lipid of Sterol Lipids (ST) class. Cucurbitacin b is associated with abnormalities such as Morphologically altered structure. The involved functions are known as Signal Transduction, Apoptosis, Cell Cycle Arrest, Cell Cycle and Negative Regulation of Mitosis. Cucurbitacin b often locates in Mediastinum and Pseudopodia. The associated genes with Cucurbitacin B are STAT5A gene, JAK2 gene, STAT3 gene, CDKN1A gene and BCL2L1 gene. The related experimental models are Xenograft Model.

References related to abnormalities published in Cancer Res.


PMIDJournalPublished DateAuthorTitle
19605406Cancer Res.2009Thoennissen NH et al.Cucurbitacin B induces apoptosis by inhibition of the JAK/STAT pathway and potentiates antiproliferative effects of gemcitabine on pancreatic cancer cells.