Lycopene

Lycopene is a lipid of Prenol Lipids (PR) class. Lycopene is associated with abnormalities such as Consumption-archaic term for TB, Chronic disease, Dehydration, furuncle and Cardiovascular Diseases. The involved functions are known as Cell Differentiation process, Signal Transduction, Biochemical Pathway, Mutation and IGF-1 Signaling Pathway. Lycopene often locates in Body tissue, Hepatic, Blood, Adipose tissue and Structure of parenchyma of lung. The associated genes with Lycopene are EPB41L2 gene, VEGFB gene, P4HTM gene, FATE1 gene and SLC33A1 gene. The related lipids are Micelles, Liposomes, Total cholesterol, Steroids and apo-10'-lycopenoic acid. The related experimental models are Mouse Model, Knock-out, Cancer Model, Transgenic Model and Xenograft Model.

References related to locations published in Carcinogenesis

PMID	Journal	Published Date	Author	Title
11238188	Carcinogenesis	2001	Imaida K et al.	Lack of chemopreventive effects of lycopene and curcumin on experimental rat prostate carcinogenesis.
15308586	Carcinogenesis	2004	Briviba K et al.	Effects of supplementing a low-carotenoid diet with a tomato extract for 2 weeks on endogenous levels of DNA single strand breaks and immune functions in healthy non-smokers and smokers.
20699249	Carcinogenesis	2010	Palozza P et al.	Lycopene induces cell growth inhibition by altering mevalonate pathway and Ras signaling in cancer cell lines.
17420169	Carcinogenesis	2007	Lian F et al.	Apo-10'-lycopenoic acid inhibits lung cancer cell growth in vitro, and suppresses lung tumorigenesis in the A/J mouse model in vivo.
18283040	Carcinogenesis	2008	Liu X et al.	Lycopene inhibits IGF-I signal transduction and growth in normal prostate epithelial cells by decreasing DHT-modulated IGF-I production in co-cultured reactive stromal cells.