quercetin

quercetin is a lipid of Polyketides (PK) class. Quercetin is associated with abnormalities such as Coronary heart disease, Myocardial Infarction, Cirrhosis, Coronary Arteriosclerosis and Vascular ring. The involved functions are known as Vasodilation, physiological aspects, Fermentation, Process and Ingredient. Quercetin often locates in Arterial system, Endothelium, Skin, Endothelium, Vascular and Tissue specimen. The associated genes with quercetin are P4HTM gene, SULT gene, UGT1A1 gene, ARHGAP26 gene and PLXNB1 gene. The related lipids are blood lipid, Promega, Steroids, Phosphatidylserines and Fatty Acids. The related experimental models are Knock-out, Mouse Model, Xenograft Model, Tissue Model and Cancer Model.

References related to functions published in Carcinogenesis

PMID	Journal	Published Date	Author	Title
11408351	Carcinogenesis	2001	Beniston RG et al.	Quercetin, E7 and p53 in papillomavirus oncogenic cell transformation.
12949046	Carcinogenesis	2003	Bacon JR et al.	Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes.
10783313	Carcinogenesis	2000	Mahmoud NN et al.	Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis.
10964096	Carcinogenesis	2000	Yang K et al.	Chemoprevention studies of the flavonoids quercetin and rutin in normal and azoxymethane-treated mouse colon.
15155531	Carcinogenesis	2004	Cheong E et al.	Synthetic and naturally occurring COX-2 inhibitors suppress proliferation in a human oesophageal adenocarcinoma cell line (OE33) by inducing apoptosis and cell cycle arrest.
14688022	Carcinogenesis	2004	Nguyen TT et al.	The role of activated MEK-ERK pathway in quercetin-induced growth inhibition and apoptosis in A549 lung cancer cells.
20044584	Carcinogenesis	2010	Lam TK et al.	Dietary quercetin, quercetin-gene interaction, metabolic gene expression in lung tissue and lung cancer risk.
17548900	Carcinogenesis	2007	Chen W et al.	Induction of death receptor 5 and suppression of survivin contribute to sensitization of TRAIL-induced cytotoxicity by quercetin in non-small cell lung cancer cells.
17548901	Carcinogenesis	2007	Rubio S et al.	Acetyl derivative of quercetin 3-methyl ether-induced cell death in human leukemia cells is amplified by the inhibition of ERK.
15661808	Carcinogenesis	2005	Yuan H et al.	Involvement of transcription factor Sp1 in quercetin-mediated inhibitory effect on the androgen receptor in human prostate cancer cells.
17148506	Carcinogenesis	2007	Psahoulia FH et al.	Quercetin mediates preferential degradation of oncogenic Ras and causes autophagy in Ha-RAS-transformed human colon cells.
16777995	Carcinogenesis	2007	Conklin CM et al.	Genistein and quercetin increase connexin43 and suppress growth of breast cancer cells.
18628248	Carcinogenesis	2008	Lin CW et al.	Quercetin inhibition of tumor invasion via suppressing PKC delta/ERK/AP-1-dependent matrix metalloproteinase-9 activation in breast carcinoma cells.