20-hydroxyecdysone

20-hydroxyecdysone is a lipid of Sterol Lipids (ST) class. 20-hydroxyecdysone is associated with abnormalities such as Congenital Abnormality, Obesity, Diabetes, Varicosity and Gilbert Disease. The involved functions are known as Binding (Molecular Function), Anabolism, Embryonic Development, Signal Transduction and Transcriptional Activation. 20-hydroxyecdysone often locates in Epidermis, Epithelium, Body tissue, Head and Blood. The associated genes with 20-hydroxyecdysone are GBGT1 gene, Homologous Gene, Genome, MMRN1 gene and Orthologous Gene. The related lipids are Steroids, muristerone, makisterone, Sterols and Liposomes.

References related to functions published in Development

PMID	Journal	Published Date	Author	Title
11585799	Development	2001	Renault N et al.	Downregulation of the tissue-specific transcription factor Fork head by Broad-Complex mediates a stage-specific hormone response.
11923209	Development	2002	Kozlova T and Thummel CS	Spatial patterns of ecdysteroid receptor activation during the onset of Drosophila metamorphosis.
20023167	Development	2010	Ruaud AF et al.	The Drosophila nuclear receptors DHR3 and betaFTZ-F1 control overlapping developmental responses in late embryos.
16368930	Development	2006	Tonning A et al.	Hormonal regulation of mummy is needed for apical extracellular matrix formation and epithelial morphogenesis in Drosophila.
22510985	Development	2012	Chawla G and Sokol NS	Hormonal activation of let-7-C microRNAs via EcR is required for adult Drosophila melanogaster morphology and function.
17804599	Development	2007	Huang X et al.	Drosophila Niemann-Pick type C-2 genes control sterol homeostasis and steroid biosynthesis: a model of human neurodegenerative disease.
26893349	Development	2016	Cai MJ et al.	20-Hydroxyecdysone activates Forkhead box O to promote proteolysis during Helicoverpa armigera molting.