stearic acid
stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
References related to abnormalities published in Diabetes
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 12663471 | Diabetes | 2003 | Eitel K et al. | Protein kinase C delta activation and translocation to the nucleus are required for fatty acid-induced apoptosis of insulin-secreting cells. |
| 12606504 | Diabetes | 2003 | Weigert C et al. | Palmitate-induced activation of the hexosamine pathway in human myotubes: increased expression of glutamine:fructose-6-phosphate aminotransferase. |
| 12031970 | Diabetes | 2002 | Dobbins RL et al. | The composition of dietary fat directly influences glucose-stimulated insulin secretion in rats. |
| 19934003 | Diabetes | 2010 | Yeop Han C et al. | Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation. |
| 20200316 | Diabetes | 2010 | Mas S et al. | Local non-esterified fatty acids correlate with inflammation in atheroma plaques of patients with type 2 diabetes. |
| 19651814 | Diabetes | 2009 | Kantartzis K et al. | Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene. |
| 19478146 | Diabetes | 2009 | Peter A et al. | Individual stearoyl-coa desaturase 1 expression modulates endoplasmic reticulum stress and inflammation in human myotubes and is associated with skeletal muscle lipid storage and insulin sensitivity in vivo. |
| 19478144 | Diabetes | 2009 | Ussher JR et al. | Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase. |
| 18633101 | Diabetes | 2008 | Reyna SM et al. | Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects. |