FLAVONE is a lipid of Polyketides (PK) class. Flavone is associated with abnormalities such as Cardiovascular Diseases, Cerebrovascular accident, DERMATITIS HERPETIFORMIS, FAMILIAL, Hyperinsulinism and Inflammatory disorder. The involved functions are known as Oxidation-Reduction, Metabolic Inhibition, Inflammation, Phosphorylation and antioxidant activity. Flavone often locates in Endothelium, Hepatic, Protoplasm, Body tissue and Extracellular. The associated genes with FLAVONE are ICAM1 gene, BCL2L1 gene, MYC gene, TP53 gene and cytochrome c''. The related lipids are Promega, Steroids and Total cholesterol. The related experimental models are Knock-out, Disease model and Animal Disease Models.
PMID | Journal | Published Date | Author | Title |
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16443668 | Drug Metab. Dispos. | 2006 | Kim SK et al. | The mitogen-activated protein kinase kinase (mek) inhibitor PD98059 elevates primary cultured rat hepatocyte glutathione levels independent of inhibiting mek. |
19074529 | Drug Metab. Dispos. | 2009 | Si D et al. | Mechanism of CYP2C9 inhibition by flavones and flavonols. |
20843940 | Drug Metab. Dispos. | 2010 | Chen EP et al. | A mechanism-based mathematical model of aryl hydrocarbon receptor-mediated CYP1A induction in rats using beta-naphthoflavone as a tool compound. |
17664249 | Drug Metab. Dispos. | 2007 | Pham MH et al. | Identification of new flavone-8-acetic acid metabolites using mouse microsomes and comparison with human microsomes. |