hypericin

hypericin is a lipid of Polyketides (PK) class. Hypericin is associated with abnormalities such as Dermatitis, Phototoxic, Dehydration, Photosensitization, Morphologically altered structure and Myocardial Infarction. The involved functions are known as Cell Cycle Checkpoints, Apoptosis, Acetylation, Cell Survival and Caspase Activation. Hypericin often locates in insoluble fraction, Cytoplasmic matrix, Protoplasm, Tissue membrane and Cytoplasm. The associated genes with hypericin are CDC37 gene, HSPA8 gene, RAF1 gene, cyclin H and FK228. The related lipids are Phosphatidylserines.

References related to functions published in Drug Metab. Dispos.


PMIDJournalPublished DateAuthorTitle
15640377Drug Metab. Dispos.2005Tian R et al.Functional induction and de-induction of P-glycoprotein by St. John's wort and its ingredients in a human colon adenocarcinoma cell line.