lauric acid
lauric acid is a lipid of Fatty Acyls (FA) class. Lauric acid is associated with abnormalities such as Infection, Renal tubular disorder, Hypertensive disease, Obesity and Mycoses. The involved functions are known as Transcription, Genetic, Signal Transduction, Mutation, metaplastic cell transformation and Anabolism. Lauric acid often locates in Skin, Plasma membrane, Cytoplasmic matrix, Body tissue and Palmar surface. The associated genes with lauric acid are Gene Family, SLC33A1 gene, Homologous Gene, Open Reading Frames and P4HTM gene. The related lipids are Fatty Acids, Oleic Acids, Palmitates, Stearates and 9,11-linoleic acid.
References related to functions published in Drug Metab. Dispos.
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 9321521 | Drug Metab. Dispos. | 1997 | Buhler DR et al. | The regiospecific hydroxylation of lauric acid by rainbow trout (Oncorhynchus mykiss) cytochrome P450s. |
| 11038153 | Drug Metab. Dispos. | 2000 | Yang YH et al. | Heterologous expression of CYP2K1 and identification of the expressed protein (BV-CYP2K1) as lauric acid (omega-1)-hydroxylase and aflatoxin B1 exo-epoxidase. |
| 15205388 | Drug Metab. Dispos. | 2004 | Poloyac SM et al. | The effect of isoniazid on CYP2E1- and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney. |
| 19196839 | Drug Metab. Dispos. | 2009 | Grillo MP and Lohr MT | Covalent binding of phenylacetic acid to protein in incubations with freshly isolated rat hepatocytes. |
| 19786506 | Drug Metab. Dispos. | 2010 | Grillo MP et al. | Stereoselective flunoxaprofen-S-acyl-glutathione thioester formation mediated by acyl-CoA formation in rat hepatocytes. |
| 15879494 | Drug Metab. Dispos. | 2005 | Minn AL et al. | Characterization of microsomal cytochrome P450-dependent monooxygenases in the rat olfactory mucosa. |