erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

References related to genes published in Drug Metab. Dispos.


PMIDJournalPublished DateAuthorTitle
9806945Drug Metab. Dispos.1998Yamazaki H and Shimada TComparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin.
12814962Drug Metab. Dispos.2003Evans DC et al.Eletriptan metabolism by human hepatic CYP450 enzymes and transport by human P-glycoprotein.
19741038Drug Metab. Dispos.2009Lan T et al.Interaction of macrolide antibiotics with intestinally expressed human and rat organic anion-transporting polypeptides.
18420780Drug Metab. Dispos.2008McLaughlin LA et al.Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.
16679385Drug Metab. Dispos.2006McGinnity DF et al.Evaluation of time-dependent cytochrome P450 inhibition using cultured human hepatocytes.