Ergosterol

Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.

References related to genes published in Eukaryotic Cell

PMID	Journal	Published Date	Author	Title
12684380	Eukaryotic Cell	2003	Hand RA et al.	Saccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptor.
12477804	Eukaryotic Cell	2002	Henry KW et al.	ROX1 and ERG regulation in Saccharomyces cerevisiae: implications for antifungal susceptibility.
15189988	Eukaryotic Cell	2004	Martin SW and Konopka JB	Lipid raft polarization contributes to hyphal growth in Candida albicans.
20870877	Eukaryotic Cell	2010	Synnott JM et al.	Regulation of the hypoxic response in Candida albicans.
22080454	Eukaryotic Cell	2012	Song MH et al.	A flucytosine-responsive Mbp1/Swi4-like protein, Mbs1, plays pleiotropic roles in antifungal drug resistance, stress response, and virulence of Cryptococcus neoformans.
17993571	Eukaryotic Cell	2008	Banerjee D et al.	Responses of pathogenic and nonpathogenic yeast species to steroids reveal the functioning and evolution of multidrug resistance transcriptional networks.
16757742	Eukaryotic Cell	2006	Grossmann G et al.	Lipid raft-based membrane compartmentation of a plant transport protein expressed in Saccharomyces cerevisiae.
18487346	Eukaryotic Cell	2008	Dunkel N et al.	A gain-of-function mutation in the transcription factor Upc2p causes upregulation of ergosterol biosynthesis genes and increased fluconazole resistance in a clinical Candida albicans isolate.
22923048	Eukaryotic Cell	2012	Flowers SA et al.	Gain-of-function mutations in UPC2 are a frequent cause of ERG11 upregulation in azole-resistant clinical isolates of Candida albicans.
26116213	Eukaryotic Cell	2015	Bühler N et al.	Functional Analysis of Sterol Transporter Orthologues in the Filamentous Fungus Aspergillus nidulans.
25084864	Eukaryotic Cell	2014	Van Hauwenhuyse F et al.	Ascorbic acid inhibition of Candida albicans Hsp90-mediated morphogenesis occurs via the transcriptional regulator Upc2.