Prostaglandin E2

Prostaglandin E2 is a lipid of Fatty Acyls (FA) class. Prostaglandin e2 is associated with abnormalities such as Renal glomerular disease, Arthritis, Degenerative polyarthritis, Pancreatitis and Rheumatoid Arthritis. The involved functions are known as enzyme pathway, Atherogenesis, Anabolism, inhibitors and Oxidants. Prostaglandin e2 often locates in Tissue membrane, Blood, Extracellular, Membrane and Protoplasm. The associated genes with Prostaglandin E2 are PTGS2 gene, TP53 gene, TNFRSF5 gene, FASTK Gene and TNF gene. The related lipids are Lipopolysaccharides, Steroids, monooxyethylene trimethylolpropane tristearate, Fatty Acids, Unsaturated and Promega. The related experimental models are Arthritis, Adjuvant-Induced, Xenograft Model, Experimental Autoimmune Encephalomyelitis, Cancer Model and Knock-out.

References related to genes published in Eur. J. Pharmacol.

PMID	Journal	Published Date	Author	Title
14751415	Eur. J. Pharmacol.	2004	Warzecha Z et al.	Inhibition of cyclooxygenase-2 reduces the protective effect of hepatocyte growth factor in experimental pancreatitis.
27108790	Eur. J. Pharmacol.	2016	Rumzhum NN and Ammit AJ	Prostaglandin E2 induces expression of MAPK phosphatase 1 (MKP-1) in airway smooth muscle cells.
26524410	Eur. J. Pharmacol.	2015	Wen Q et al.	Des-aspartate-angiotensin I causes specific release of PGE2 and PGI2 in HUVEC via the angiotensin AT1 receptor and biased agonism.
26415983	Eur. J. Pharmacol.	2015	Li Y et al.	Regulation of PGE2 signaling pathways and TNF-alpha signaling pathways on the function of bone marrow-derived dendritic cells and the effects of CP-25.
24211328	Eur. J. Pharmacol.	2013	Magnone M et al.	Fluridone as a new anti-inflammatory drug.
22713546	Eur. J. Pharmacol.	2012	Hsu YH et al.	Long-term leptin treatment exerts a pro-apoptotic effect on renal tubular cells via prostaglandin E2 augmentation.
20361960	Eur. J. Pharmacol.	2010	Zrieki A et al.	Cyclooxygenase-2 inhibitors prevent trinitrobenzene sulfonic acid-induced P-glycoprotein up-regulation in vitro and in vivo.
15840408	Eur. J. Pharmacol.	2005	Takahashi HK et al.	Differential effect of prostaglandins E1 and E2 on lipopolysaccharide-induced adhesion molecule expression on human monocytes.
10594346	Eur. J. Pharmacol.	1999	Yamada R et al.	Auranofin inhibits interleukin-1beta-induced transcript of cyclooxygenase-2 on cultured human synoviocytes.
10422646	Eur. J. Pharmacol.	1999	Marquet F et al.	Distant intestinal stimulation by cholera toxin in rat in vivo.
9761426	Eur. J. Pharmacol.	1998	Shimada K et al.	Cyclooxygenase 2 expression by endothelin-1-stimulated mouse resident peritoneal macrophages in vitro.