PGD2

Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.

References related to abnormalities published in J. Allergy Clin. Immunol.


PMIDJournalPublished DateAuthorTitle
27423494J. Allergy Clin. Immunol.2016Feng X et al.Eosinophil production of prostaglandin D2 in patients with aspirin-exacerbated respiratory disease.
26792210J. Allergy Clin. Immunol.2016Jandl K et al.Activated prostaglandin D2 receptors on macrophages enhance neutrophil recruitment into the lung.
26691435J. Allergy Clin. Immunol.2016Buchheit KM et al.Thymic stromal lymphopoietin controls prostaglandin D2 generation in patients with aspirin-exacerbated respiratory disease.
25441644J. Allergy Clin. Immunol.2015Xue L et al.Prostaglandin D2 and leukotriene E4 synergize to stimulate diverse TH2 functions and TH2 cell/neutrophil crosstalk.