20-HETE
20-hete is a lipid of Fatty Acyls (FA) class. 20-hete is associated with abnormalities such as Cyst, Kidney Diseases, Kidney Failure, Chronic, Cystic Kidney Diseases and Simple renal cyst. The involved functions are known as Phosphorylation, inhibitors, Hypertrophy, Epithelial Cell Proliferation and Anabolism. 20-hete often locates in Mouse Kidney, Microsomes, Tissue membrane, Body tissue and Cytoplasmic matrix. The associated genes with 20-HETE are CYP4F3 gene, PKHD1 gene, Transgenes, P4HTM gene and CYP2E1 gene. The related lipids are Promega, enterodiol, Fatty Acids, hexanoic acid and U 73343. The related experimental models are Mouse Model, Knock-out, Streptozotocin Diabetes, Transgenic Model and Rodent Model.
References related to experimental models published in J. Am. Soc. Nephrol.
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 18596124 | J. Am. Soc. Nephrol. | 2008 | Park F et al. | 20-HETE mediates proliferation of renal epithelial cells in polycystic kidney disease. |
| 25071086 | J. Am. Soc. Nephrol. | 2015 | Gangadhariah MH et al. | Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy. |