clarithromycin

clarithromycin is a lipid of Polyketides (PK) class. Clarithromycin is associated with abnormalities such as Helicobacter Pylori Infection, Infection, Coinfection, Gastritis and Peptic Ulcer. The involved functions are known as Point Mutation, Increased Sensitivy, Bacterial resistance, urease activity and Mutation. Clarithromycin often locates in Blood, Gastric mucosa, Biopsy sample, Respiratory System and Entire gastrointestinal tract. The associated genes with clarithromycin are Genes, rRNA, rRNA Operon, Genome, HM13 gene and GDF15 gene. The related lipids are 9,11-linoleic acid, Steroids, Lysophosphatidylcholines, Lipopolysaccharides and 4-hydroxycholesterol. The related experimental models are Mouse Model, Knock-out and Experimental Pneumococcal Meningitis.

References related to functions published in J. Antimicrob. Chemother.

PMID	Journal	Published Date	Author	Title
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11266411	J. Antimicrob. Chemother.	2001	Endo H et al.	Effects of lansoprazole, clarithromycin and pH gradient on uptake of [14C]amoxycillin into rat gastric tissue.
12161414	J. Antimicrob. Chemother.	2002	Endo H et al.	Localization of [14C]clarithromycin in rat gastric tissue when administered with lansoprazole and amoxicillin.
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12461005	J. Antimicrob. Chemother.	2002	Matysiak-Budnik T et al.	In vitro transfer of clarithromycin and amoxicillin across the epithelial barrier: effect of Helicobacter pylori.
12888589	J. Antimicrob. Chemother.	2003	Gotfried MH et al.	Steady-state plasma and bronchopulmonary characteristics of clarithromycin extended-release tablets in normal healthy adult subjects.
10747833	J. Antimicrob. Chemother.	2000	Paton R et al.	Susceptibility testing of Haemophilus influenzae to clarithromycin.
10933651	J. Antimicrob. Chemother.	2000	Theron AJ et al.	Investigation of the anti-inflammatory and membrane-stabilizing potential of spiramycin in vitro.
10980165	J. Antimicrob. Chemother.	2000	Bosne-David S et al.	Intrinsic resistance of Mycobacterium tuberculosis to clarithromycin is effectively reversed by subinhibitory concentrations of cell wall inhibitors.
11020255	J. Antimicrob. Chemother.	2000	Cirioni O et al.	Inhibition of growth of Pneumocystis carinii by lactoferrins alone and in combination with pyrimethamine, clarithromycin and minocycline.
11020260	J. Antimicrob. Chemother.	2000	Alarcón T et al.	Clarithromycin resistance stability in Helicobacter pylori: influence of the MIC and type of mutation in the 23S rRNA.
10882691	J. Antimicrob. Chemother.	2000	Yanagihara K et al.	Combination therapy for chronic Pseudomonas aeruginosa respiratory infection associated with biofilm formation.
10702548	J. Antimicrob. Chemother.	2000	Ives TJ et al.	In vitro susceptibilities of Rickettsia and Bartonella spp. to 14-hydroxy-clarithromycin as determined by immunofluorescent antibody analysis of infected vero cell monolayers.
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21393190	J. Antimicrob. Chemother.	2011	Inagaki T et al.	Evaluation of a rapid detection method of clarithromycin resistance genes in Mycobacterium avium complex isolates.
21406436	J. Antimicrob. Chemother.	2011	Cirioni O et al.	Effect of the combination of clarithromycin and amikacin on Pseudomonas aeruginosa biofilm in an animal model of ureteral stent infection.
19477891	J. Antimicrob. Chemother.	2009	Jespersen CM et al.	Compliance with and short-term adverse events from clarithromycin versus placebo in patients with stable coronary heart disease: the CLARICOR trial.
20008044	J. Antimicrob. Chemother.	2010	De Francesco V et al.	Phenotypic and genotypic Helicobacter pylori clarithromycin resistance and therapeutic outcome: benefits and limits.
17329269	J. Antimicrob. Chemother.	2007	De Francesco V et al.	Prevalence of primary clarithromycin resistance in Helicobacter pylori strains over a 15 year period in Italy.
21764826	J. Antimicrob. Chemother.	2011	Oleastro M et al.	Primary antibiotic resistance of Helicobacter pylori strains isolated from Portuguese children: a prospective multicentre study over a 10 year period.
21791441	J. Antimicrob. Chemother.	2011	Tagliabue C et al.	Efficacy of increasing dosages of clarithromycin for treatment of experimental Mycoplasma pneumoniae pneumonia.
17412724	J. Antimicrob. Chemother.	2007	Shinkai M et al.	Clarithromycin has an immunomodulatory effect on ERK-mediated inflammation induced by Pseudomonas aeruginosa flagellin.
17827146	J. Antimicrob. Chemother.	2007	Sasaki M et al.	Effect of plaunotol in combination with clarithromycin against clarithromycin-resistant Helicobacter pylori in vitro and in vivo.
16303883	J. Antimicrob. Chemother.	2006	Cai S et al.	Antimicrobial activity of picolinic acid against extracellular and intracellular Mycobacterium avium complex and its combined activity with clarithromycin, rifampicin and fluoroquinolones.
16024590	J. Antimicrob. Chemother.	2005	Sun HK et al.	Efficacy of pulsatile amoxicillin and clarithromycin dosing alone and in combination in a murine pneumococcal pneumonia model.
16006447	J. Antimicrob. Chemother.	2005	Williams AC et al.	Differential effects of three antibiotics on T helper cell cytokine expression.
16549515	J. Antimicrob. Chemother.	2006	Giamarellos-Bourboulis EJ et al.	Clarithromycin is an effective immunomodulator in experimental pyelonephritis caused by pan-resistant Klebsiella pneumoniae.
17218449	J. Antimicrob. Chemother.	2007	Anderson R et al.	Clarithromycin alone and in combination with ceftriaxone inhibits the production of pneumolysin by both macrolide-susceptible and macrolide-resistant strains of Streptococcus pneumoniae.
17208955	J. Antimicrob. Chemother.	2007	Ozsoylar G et al.	Clarithromycin monotherapy-induced delirium.
22833642	J. Antimicrob. Chemother.	2012	Maurer FP et al.	Acquisition of clarithromycin resistance mutations in the 23S rRNA gene of Mycobacterium abscessus in the presence of inducible erm(41).