nystatin

nystatin is a lipid of Polyketides (PK) class. Nystatin is associated with abnormalities such as Virus Diseases, Infection, Candidiasis, Leukopenia and Mycoses. The involved functions are known as Membrane Potentials, Uptake, Flow or discharge, Cell membrane potential and adenine transport. Nystatin often locates in Cell Wall, Plasma membrane, Extracellular, Membrane and Virion. The associated genes with nystatin are Genome, Integral Membrane Proteins, Amino Acids, Basic, P4HTM gene and Homologous Gene. The related lipids are Sterols, Liposomes, Membrane Lipids, Sphingolipids and 1,2-oleoylphosphatidylcholine. The related experimental models are Knock-out and Xenograft Model.

References related to functions published in J. Antimicrob. Chemother.


PMIDJournalPublished DateAuthorTitle
10381106J. Antimicrob. Chemother.1999Groll AH et al.Liposomal nystatin against experimental pulmonary aspergillosis in persistently neutropenic rabbits: efficacy, safety and non-compartmental pharmacokinetics.
10511410J. Antimicrob. Chemother.1999Carrillo-Muñoz AJ et al.In-vitro antifungal activity of liposomal nystatin in comparison with nystatin, amphotericin B cholesteryl sulphate, liposomal amphotericin B, amphotericin B lipid complex, amphotericin B desoxycholate, fluconazole and itraconazole.
12003966J. Antimicrob. Chemother.2002Dannaoui E et al.In vitro susceptibilities of Zygomycota to polyenes.
12039882J. Antimicrob. Chemother.2002Zhang L et al.Response of gene expression in Saccharomyces cerevisiae to amphotericin B and nystatin measured by microarrays.
12775672J. Antimicrob. Chemother.2003Vitale RG et al.Evaluation of the post-antifungal effect (PAFE) of amphotericin B and nystatin against 30 zygomycetes using two different media.
18343803J. Antimicrob. Chemother.2008Oliver BG et al.Polyene susceptibility is dependent on nitrogen source in the opportunistic pathogen Candida albicans.
22499997J. Antimicrob. Chemother.2012Semis R et al.Pharmacokinetics, tissue distribution and immunomodulatory effect of intralipid formulation of nystatin in mice.
23620465J. Antimicrob. Chemother.2013Melkoumov A et al.Nystatin nanosizing enhances in vitro and in vivo antifungal activity against Candida albicans.