erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

References related to genes published in J. Antimicrob. Chemother.


PMIDJournalPublished DateAuthorTitle
11328768J. Antimicrob. Chemother.2001Martin SJ et al.The activity of 14-hydroxy clarithromycin, alone and in combination with clarithromycin, against penicillin- and erythromycin-resistant Streptococcus pneumoniae.
11328778J. Antimicrob. Chemother.2001Zarantonelli L et al.Decreased susceptibility to azithromycin and erythromycin mediated by a novel mtr(R) promoter mutation in Neisseria gonorrhoeae.
11020257J. Antimicrob. Chemother.2000Takemura H et al.Evaluation of a human monocytic cell line THP-1 model for assay of the intracellular activities of antimicrobial agents against Legionella pneumophila.
15243030J. Antimicrob. Chemother.2004Peric M et al.Inability of L22 ribosomal protein alteration to increase macrolide MICs in the absence of efflux mechanism in Haemophilus influenzae HMC-S.
19131424J. Antimicrob. Chemother.2009Liu J et al.Characterization of a novel macrolide efflux gene, mef(B), found linked to sul3 in porcine Escherichia coli.
19584106J. Antimicrob. Chemother.2009Tazumi A et al.Molecular characterization of macrolide resistance determinants [erm(B) and mef(A)] in Streptococcus pneumoniae and viridans group streptococci (VGS) isolated from adult patients with cystic fibrosis (CF).
15590715J. Antimicrob. Chemother.2005Amsden GWAnti-inflammatory effects of macrolides--an underappreciated benefit in the treatment of community-acquired respiratory tract infections and chronic inflammatory pulmonary conditions?
15531597J. Antimicrob. Chemother.2004Dias R and Caniça MEmergence of invasive erythromycin-resistant Streptococcus pneumoniae strains in Portugal: contribution and phylogenetic relatedness of serotype 14.
16464889J. Antimicrob. Chemother.2006Pereyre S et al.Emergence of a 23S rRNA mutation in Mycoplasma hominis associated with a loss of the intrinsic resistance to erythromycin and azithromycin.
16162665J. Antimicrob. Chemother.2005Rouquette-Loughlin CE et al.Characterization of the MacA-MacB efflux system in Neisseria gonorrhoeae.