Ergosterol

Ergosterol is a lipid of Sterol Lipids (ST) class. Ergosterol is associated with abnormalities such as Disintegration (morphologic abnormality), Consumption-archaic term for TB, Candidiasis, Mycoses and Iodotyrosyl coupling defect. The involved functions are known as Anabolism, sporulation, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Subtraction process and Physiologic Organization. Ergosterol often locates in Pore, Membrane, Protoplasm, Plasma membrane and Endoplasmic Reticulum. The associated genes with Ergosterol are IMPACT gene, BLVRB gene, CYP51A1 gene, CDR1 wt Allele and HM13 gene. The related lipids are Sterols, Cardiolipins, Membrane Lipids, fecosterol and Phosphatidylserines. The related experimental models are Knock-out.

References related to lipids published in J. Antimicrob. Chemother.


PMIDJournalPublished DateAuthorTitle
10404315J. Antimicrob. Chemother.1999Siau H and Kerridge D5-Fluorocytosine antagonizes the action of sterol biosynthesis inhibitors in Candida glabrata.
10382888J. Antimicrob. Chemother.1999Park KS et al.Differential inhibitory effects of protoberberines on sterol and chitin biosyntheses in Candida albicans.
10933640J. Antimicrob. Chemother.2000Kontoyiannis DPModulation of fluconazole sensitivity by the interaction of mitochondria and erg3p in Saccharomyces cerevisiae.
10933641J. Antimicrob. Chemother.2000Kontoyiannis DPEfflux-mediated resistance to fluconazole could be modulated by sterol homeostasis in Saccharomyces cerevisiae.
15201226J. Antimicrob. Chemother.2004Parveen M et al.Response of Saccharomyces cerevisiae to a monoterpene: evaluation of antifungal potential by DNA microarray analysis.
15201233J. Antimicrob. Chemother.2004Barker KS et al.Genome-wide expression profiling reveals genes associated with amphotericin B and fluconazole resistance in experimentally induced antifungal resistant isolates of Candida albicans.
18971215J. Antimicrob. Chemother.2009Ells R et al.Arachidonic acid increases antifungal susceptibility of Candida albicans and Candida dubliniensis.
19059942J. Antimicrob. Chemother.2009De Seta F et al.Antifungal mechanisms supporting boric acid therapy of Candida vaginitis.
15845783J. Antimicrob. Chemother.2005Pasrija R et al.Squalene epoxidase encoded by ERG1 affects morphogenesis and drug susceptibilities of Candida albicans.
23221625J. Antimicrob. Chemother.2013Jiang C et al.Mechanisms of azole resistance in 52 clinical isolates of Candida tropicalis in China.