quercetin

quercetin is a lipid of Polyketides (PK) class. Quercetin is associated with abnormalities such as Coronary heart disease, Myocardial Infarction, Cirrhosis, Coronary Arteriosclerosis and Vascular ring. The involved functions are known as Vasodilation, physiological aspects, Fermentation, Process and Ingredient. Quercetin often locates in Arterial system, Endothelium, Skin, Endothelium, Vascular and Tissue specimen. The associated genes with quercetin are P4HTM gene, SULT gene, UGT1A1 gene, ARHGAP26 gene and PLXNB1 gene. The related lipids are blood lipid, Promega, Steroids, Phosphatidylserines and Fatty Acids. The related experimental models are Knock-out, Mouse Model, Xenograft Model, Tissue Model and Cancer Model.

References related to abnormalities published in J. Biol. Chem.

PMID	Journal	Published Date	Author	Title
11834736	J. Biol. Chem.	2002	Song J et al.	Flavonoid inhibition of sodium-dependent vitamin C transporter 1 (SVCT1) and glucose transporter isoform 2 (GLUT2), intestinal transporters for vitamin C and Glucose.
12826665	J. Biol. Chem.	2003	Spencer JP et al.	Modulation of pro-survival Akt/protein kinase B and ERK1/2 signaling cascades by quercetin and its in vivo metabolites underlie their action on neuronal viability.
12517755	J. Biol. Chem.	2003	Welford RW et al.	The selectivity and inhibition of AlkB.
18032389	J. Biol. Chem.	2008	Soundararajan R et al.	Quercetin 3-glucoside protects neuroblastoma (SH-SY5Y) cells in vitro against oxidative damage by inducing sterol regulatory element-binding protein-2-mediated cholesterol biosynthesis.
18199750	J. Biol. Chem.	2008	Kawai Y et al.	Macrophage as a target of quercetin glucuronides in human atherosclerotic arteries: implication in the anti-atherosclerotic mechanism of dietary flavonoids.
16407180	J. Biol. Chem.	2006	Cunningham P et al.	Docking studies show that D-glucose and quercetin slide through the transporter GLUT1.
15456784	J. Biol. Chem.	2004	Kuo PC et al.	Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells.
16982612	J. Biol. Chem.	2006	He XZ et al.	Mutational analysis of the Medicago glycosyltransferase UGT71G1 reveals residues that control regioselectivity for (iso)flavonoid glycosylation.
23223575	J. Biol. Chem.	2013	Beazley KE et al.	Quercetin attenuates warfarin-induced vascular calcification in vitro independently from matrix Gla protein.