stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

References related to abnormalities published in J. Biol. Chem.

PMID	Journal	Published Date	Author	Title
8798573	J. Biol. Chem.	1996	Reverey H et al.	Differential fatty acid selection during biosynthetic S-acylation of a transmembrane protein (HEF) and other proteins in insect cells (Sf9) and in mammalian cells (CV1).
21697096	J. Biol. Chem.	2011	Xu M et al.	Novel functions of lipid-binding protein 5 in Caenorhabditis elegans fat metabolism.
21257748	J. Biol. Chem.	2011	Calegari VC et al.	Inflammation of the hypothalamus leads to defective pancreatic islet function.
15851470	J. Biol. Chem.	2005	Scaglia N and Igal RA	Stearoyl-CoA desaturase is involved in the control of proliferation, anchorage-independent growth, and survival in human transformed cells.
23306194	J. Biol. Chem.	2013	Lee W et al.	Intracellular Mycobacterium tuberculosis exploits host-derived fatty acids to limit metabolic stress.
20032470	J. Biol. Chem.	2010	Collins JM et al.	De novo lipogenesis and stearoyl-CoA desaturase are coordinately regulated in the human adipocyte and protect against palmitate-induced cell injury.
17416903	J. Biol. Chem.	2007	Crunkhorn S et al.	Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation.
17127673	J. Biol. Chem.	2007	Sampath H et al.	Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat.
11423543	J. Biol. Chem.	2001	Liang X et al.	Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction.