oxytetracycline

oxytetracycline is a lipid of Polyketides (PK) class. Oxytetracycline is associated with abnormalities such as Infection, X-linked centronuclear myopathy, Bacterial Infections, Heart failure and Onchocerciasis. The involved functions are known as Anabolism, physiological aspects, Transcription, Genetic, Fermentation and Transcriptional Activation. Oxytetracycline often locates in Chromosomes, Flank (surface region), Entire bony skeleton, Bone Marrow and Body tissue. The associated genes with oxytetracycline are Polypeptides, Homologous Gene, Gene Clusters, Locus and CYCS gene. The related lipids are LH 1 and Lipid Peroxides. The related experimental models are Disease model.

References related to functions published in J. Biol. Chem.


PMIDJournalPublished DateAuthorTitle
10551844J. Biol. Chem.1999Petkovic H et al.Disruption of an aromatase/cyclase from the oxytetracycline gene cluster of Streptomyces rimosus results in production of novel polyketides with shorter chain lengths.
15452119J. Biol. Chem.2004Yang W et al.TetX is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics.
20522541J. Biol. Chem.2010Pickens LB and Tang YOxytetracycline biosynthesis.
17631493J. Biol. Chem.2007Zhang W et al.Investigation of early tailoring reactions in the oxytetracycline biosynthetic pathway.
16148009J. Biol. Chem.2005Peric-Concha N et al.Ablation of the otcC gene encoding a post-polyketide hydroxylase from the oxytetracyline biosynthetic pathway in Streptomyces rimosus results in novel polyketides with altered chain length.