propionic acid

propionic acid is a lipid of Fatty Acyls (FA) class. Propionic acid is associated with abnormalities such as Epilepsy, Infection, Tuberculosis, Alkalosis and Ischemia. The involved functions are known as Uptake, Biosynthetic Pathways, Methylation, Protein Overexpression and Biochemical Pathway. Propionic acid often locates in Body tissue, Cytoplasmic matrix, Membrane, Protoplasm and Extracellular. The associated genes with propionic acid are TRIO gene, TRRAP gene, SLC5A8 gene, SLC33A1 gene and Homologous Gene. The related lipids are Fatty Acids, Propionate, butyrate, Valerates and mycocerosic acid.

References related to functions published in J. Biol. Chem.

PMID	Journal	Published Date	Author	Title
11461925	J. Biol. Chem.	2001	Miyazaki T et al.	Fatal propionic acidemia in mice lacking propionyl-CoA carboxylase and its rescue by postnatal, liver-specific supplementation via a transgene.
11278910	J. Biol. Chem.	2001	Sirakova TD et al.	The Mycobacterium tuberculosis pks2 gene encodes the synthase for the hepta- and octamethyl-branched fatty acids required for sulfolipid synthesis.
12711604	J. Biol. Chem.	2003	Le Poul E et al.	Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation.
12496283	J. Biol. Chem.	2003	Brown AJ et al.	The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.
10858451	J. Biol. Chem.	2000	Cunningham O et al.	Studies on the specificity of the tetrapyrrole substrate for human biliverdin-IXalpha reductase and biliverdin-IXbeta reductase. Structure-activity relationships define models for both active sites.
15322102	J. Biol. Chem.	2004	Gopal E et al.	Expression of slc5a8 in kidney and its role in Na(+)-coupled transport of lactate.
17580301	J. Biol. Chem.	2007	Lucas KA et al.	Peroxisomal metabolism of propionic acid and isobutyric acid in plants.
15647267	J. Biol. Chem.	2005	Kambo A et al.	Nitric oxide inhibits mammalian methylmalonyl-CoA mutase.
22582391	J. Biol. Chem.	2012	Lang C et al.	Zinc metalloproteinase ProA directly activates Legionella pneumophila PlaC glycerophospholipid:cholesterol acyltransferase.