butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

References related to functions published in J. Biol. Chem.

PMID	Journal	Published Date	Author	Title
7738018	J. Biol. Chem.	1995	Garred O et al.	Furin-induced cleavage and activation of Shiga toxin.
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9268365	J. Biol. Chem.	1997	Nakano K et al.	Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line.
9305863	J. Biol. Chem.	1997	Cuisset L et al.	The effects of sodium butyrate on transcription are mediated through activation of a protein phosphatase.
9242673	J. Biol. Chem.	1997	Ferry AE et al.	Globin gene silencing in primary erythroid cultures. An inhibitory role for interleukin-6.
9733739	J. Biol. Chem.	1998	Hendzel MJ et al.	Chromatin condensation is not associated with apoptosis.
9603965	J. Biol. Chem.	1998	Walia H et al.	Histone acetylation is required to maintain the unfolded nucleosome structure associated with transcribing DNA.
9705287	J. Biol. Chem.	1998	Kamitani H et al.	Expression of 15-lipoxygenase by human colorectal carcinoma Caco-2 cells during apoptosis and cell differentiation.
10747961	J. Biol. Chem.	2000	Courilleau D et al.	B-ind1, a novel mediator of Rac1 signaling cloned from sodium butyrate-treated fibroblasts.
10777603	J. Biol. Chem.	2000	Waterborg JH	Steady-state levels of histone acetylation in Saccharomyces cerevisiae.
10816597	J. Biol. Chem.	2000	Vilaboa NE et al.	Regulation of multidrug resistance 1 (MDR1)/P-glycoprotein gene expression and activity by heat-shock transcription factor 1 (HSF1).
10899165	J. Biol. Chem.	2000	Bai L and Merchant JL	Transcription factor ZBP-89 cooperates with histone acetyltransferase p300 during butyrate activation of p21waf1 transcription in human cells.
15044487	J. Biol. Chem.	2004	Ventura C et al.	Butyric and retinoic mixed ester of hyaluronan. A novel differentiating glycoconjugate affording a high throughput of cardiogenesis in embryonic stem cells.