Isopentenyl pyrophosphate
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
References related to functions published in J. Biol. Chem.
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 11278429 | J. Biol. Chem. | 2001 | Lafont V et al. | Isopentenyl pyrophosphate, a mycobacterial non-peptidic antigen, triggers delayed and highly sustained signaling in human gamma delta T lymphocytes without inducing eown-modulation of T cell antigen receptor. |
| 19875454 | J. Biol. Chem. | 2010 | Mitrofan LM et al. | Lysosomal-mitochondrial axis in zoledronic acid-induced apoptosis in human follicular lymphoma cells. |
| 16698791 | J. Biol. Chem. | 2006 | Kavanagh KL et al. | The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding. |
| 16554305 | J. Biol. Chem. | 2006 | Chang TH et al. | Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination. |
| 11675382 | J. Biol. Chem. | 2002 | Feurle J et al. | Escherichia coli produces phosphoantigens activating human gamma delta T cells. |