octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

References related to functions published in J. Biol. Chem.

PMID	Journal	Published Date	Author	Title
10358026	J. Biol. Chem.	1999	Gao J and Serrero G	Adipose differentiation related protein (ADRP) expressed in transfected COS-7 cells selectively stimulates long chain fatty acid uptake.
11707445	J. Biol. Chem.	2002	Frederich M and Balschi JA	The relationship between AMP-activated protein kinase activity and AMP concentration in the isolated perfused rat heart.
10801788	J. Biol. Chem.	2000	Watanabe K et al.	Constitutive regulation of cardiac fatty acid metabolism through peroxisome proliferator-activated receptor alpha associated with age-dependent cardiac toxicity.
10671542	J. Biol. Chem.	2000	Gueguen V et al.	Fatty acid and lipoic acid biosynthesis in higher plant mitochondria.
11546772	J. Biol. Chem.	2001	Kaiya H et al.	Bullfrog ghrelin is modified by n-octanoic acid at its third threonine residue.
15161924	J. Biol. Chem.	2004	Campbell SE et al.	A novel function for fatty acid translocase (FAT)/CD36: involvement in long chain fatty acid transfer into the mitochondria.
19457861	J. Biol. Chem.	2009	Guy JE et al.	Crystal structure of a class XIB phospholipase A2 (PLA2): rice (oryza sativa) isoform-2 pla2 and an octanoate complex.
17693400	J. Biol. Chem.	2007	Qahwash IM et al.	Site-specific effects of peptide lipidation on beta-amyloid aggregation and cytotoxicity.
16210327	J. Biol. Chem.	2005	Jordanova R et al.	The highly abundant protein Ag-lbp55 from Ascaridia galli represents a novel type of lipid-binding proteins.
18809675	J. Biol. Chem.	2008	Stoddart CA et al.	Albumin-conjugated C34 peptide HIV-1 fusion inhibitor: equipotent to C34 and T-20 in vitro with sustained activity in SCID-hu Thy/Liv mice.
17166831	J. Biol. Chem.	2007	Stephens JL et al.	Mitochondrial fatty acid synthesis in Trypanosoma brucei.
14523010	J. Biol. Chem.	2003	Lai CY and Cronan JE	Beta-ketoacyl-acyl carrier protein synthase III (FabH) is essential for bacterial fatty acid synthesis.
12531885	J. Biol. Chem.	2003	Beaumont NJ et al.	Ghrelin can bind to a species of high density lipoprotein associated with paraoxonase.
11724780	J. Biol. Chem.	2002	Kawaguchi T et al.	Mechanism for fatty acid "sparing" effect on glucose-induced transcription: regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase.