lanosterol

lanosterol is a lipid of Sterol Lipids (ST) class. Lanosterol is associated with abnormalities such as Infection, Atherosclerosis, Myocardial Infarction, Chagas Disease and Fatty Liver. The involved functions are known as Signal, Cytokinesis, physiological aspects, Stereochemistry and ergosterol biosynthetic process. Lanosterol often locates in Body tissue, Membrane, Plasma membrane, Tissue membrane and Cytoskeletal Filaments. The associated genes with lanosterol are Retinoic Acid Response Element, P4HTM gene, CYP51A1 gene, HM13 gene and SC4MOL gene. The related lipids are pneumocysterol, Sterols, lanosteryl acetate, ebericol and cycloartenol. The related experimental models are Knock-out.

References related to functions published in J. Biol. Chem.


PMIDJournalPublished DateAuthorTitle
22577133J. Biol. Chem.2012Iyoda T et al.Lysophosphatidic acid induces early growth response-1 (Egr-1) protein expression via protein kinase Cδ-regulated extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) activation in vascular smooth muscle cells.
8621604J. Biol. Chem.1996Shi J et al.Identification and characterization of an S-adenosyl-L-methionine: delta 24-sterol-C-methyltransferase cDNA from soybean.
17595166J. Biol. Chem.2007Hughes AL et al.4-Methyl sterols regulate fission yeast SREBP-Scap under low oxygen and cell stress.
22453923J. Biol. Chem.2012D'Agostino J et al.Potential biological functions of cytochrome P450 reductase-dependent enzymes in small intestine: novel link to expression of major histocompatibility complex class II genes.
22147702J. Biol. Chem.2012Shichiri M et al.A novel role for α-tocopherol transfer protein (α-TTP) in protecting against chloroquine toxicity.
12235134J. Biol. Chem.2002Jackson CJ et al.A novel sterol 14alpha-demethylase/ferredoxin fusion protein (MCCYP51FX) from Methylococcus capsulatus represents a new class of the cytochrome P450 superfamily.