Ecdysone

Ecdysone is a lipid of Sterol Lipids (ST) class. Ecdysone is associated with abnormalities such as Lafora Disease, Congenital Abnormality, Infection, protrusion and Morphologically altered structure. The involved functions are known as Cardiac Arrest, Transcription, Genetic, receptor function, Stimulus and Signal Transduction. Ecdysone often locates in Body tissue, Chromosomes, Polytene Chromosome, Epidermis and Muscle. The associated genes with Ecdysone are FATE1 gene, LGALS4 gene, Transgenes, LacZ Genes and C10orf27 gene. The related lipids are Steroids, FuGene, muristerone, N,N-dimethyl-N-hexadecyl-1-octadecylammonium chloride and 7-dehydrocholesterol. The related experimental models are Tissue Model.

References related to functions published in J. Biol. Chem.

PMID	Journal	Published Date	Author	Title
21602274	J. Biol. Chem.	2011	Kim EK et al.	Activation of AMP-activated protein kinase is essential for lysophosphatidic acid-induced cell migration in ovarian cancer cells.
9765285	J. Biol. Chem.	1998	Wang SF et al.	DNA binding and transactivation characteristics of the mosquito ecdysone receptor-Ultraspiracle complex.
10722717	J. Biol. Chem.	2000	Kang JS and Kim JS	Zinc finger proteins as designer transcription factors.
15107428	J. Biol. Chem.	2004	Kumar MB et al.	Highly flexible ligand binding pocket of ecdysone receptor: a single amino acid change leads to discrimination between two groups of nonsteroidal ecdysone agonists.
19996319	J. Biol. Chem.	2010	Bellemare J et al.	Modulation of the human glucuronosyltransferase UGT1A pathway by splice isoform polypeptides is mediated through protein-protein interactions.
14976192	J. Biol. Chem.	2004	Cakouros D et al.	An arginine-histone methyltransferase, CARMER, coordinates ecdysone-mediated apoptosis in Drosophila cells.
15657059	J. Biol. Chem.	2005	Kilpatrick ZE et al.	Ecdysone-mediated up-regulation of the effector caspase DRICE is required for hormone-dependent apoptosis in Drosophila cells.
15701625	J. Biol. Chem.	2005	Yamanaka N et al.	Identification of a novel prothoracicostatic hormone and its receptor in the silkworm Bombyx mori.
16990270	J. Biol. Chem.	2006	Zraly CB et al.	Hormone-response genes are direct in vivo regulatory targets of Brahma (SWI/SNF) complex function.
22427652	J. Biol. Chem.	2012	Kamimura M et al.	Fungal ecdysteroid-22-oxidase, a new tool for manipulating ecdysteroid signaling and insect development.
12721294	J. Biol. Chem.	2003	Yamada R and Sonobe H	Purification, kinetic characterization, and molecular cloning of a novel enzyme ecdysteroid-phosphate phosphatase.
17956872	J. Biol. Chem.	2007	Li Y et al.	Identification and characterization of a juvenile hormone response element and its binding proteins.
15809296	J. Biol. Chem.	2005	Carmichael JA et al.	The X-ray structure of a hemipteran ecdysone receptor ligand-binding domain: comparison with a lepidopteran ecdysone receptor ligand-binding domain and implications for insecticide design.
11375999	J. Biol. Chem.	2001	Lee-Kwon W et al.	Constitutively active phosphatidylinositol 3-kinase and AKT are sufficient to stimulate the epithelial Na+/H+ exchanger 3.
11053444	J. Biol. Chem.	2001	Billas IM et al.	Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects.
26253172	J. Biol. Chem.	2015	Meng M et al.	The homeodomain transcription factors antennapedia and POU-M2 regulate the transcription of the steroidogenic enzyme gene Phantom in the silkworm.