lipoamide

Lipoamide is a lipid of Fatty Acyls (FA) class. Lipoamide is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Phosphorylation, Protonation, Mutagenesis, Site-Directed, Oxidants and Acetylation. Lipoamide often locates in Mitochondria, Mitochondrial matrix, nucleocapsid location and Chloroplasts. The associated genes with lipoamide are Mutant Proteins, Recombinant Proteins, mycothione reductase, alanylproline and Genes, Mitochondrial.

References related to functions published in J. Biol. Chem.

PMID	Journal	Published Date	Author	Title
12902323	J. Biol. Chem.	2003	Wynn RM et al.	Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase: refined phosphorylation loop structure in the active site.
17565998	J. Biol. Chem.	2007	Gazaryan IG et al.	Zinc irreversibly damages major enzymes of energy production and antioxidant defense prior to mitochondrial permeability transition.
16093239	J. Biol. Chem.	2005	Rajashankar KR et al.	Crystal structure and functional analysis of lipoamide dehydrogenase from Mycobacterium tuberculosis.
15710613	J. Biol. Chem.	2005	Klyachko NL et al.	pH-dependent substrate preference of pig heart lipoamide dehydrogenase varies with oligomeric state: response to mitochondrial matrix acidification.
15456792	J. Biol. Chem.	2004	Argyrou A et al.	Characterization of a new member of the flavoprotein disulfide reductase family of enzymes from Mycobacterium tuberculosis.
14555654	J. Biol. Chem.	2004	Bafunno V et al.	Riboflavin uptake and FAD synthesis in Saccharomyces cerevisiae mitochondria: involvement of the Flx1p carrier in FAD export.
12651851	J. Biol. Chem.	2003	Ciszak EM et al.	Structural basis for flip-flop action of thiamin pyrophosphate-dependent enzymes revealed by human pyruvate dehydrogenase.
11744691	J. Biol. Chem.	2002	Gazaryan IG et al.	Zinc is a potent inhibitor of thiol oxidoreductase activity and stimulates reactive oxygen species production by lipoamide dehydrogenase.