18194-24-6

18194-24-6 is a lipid of Glycerophospholipids (GP) class. 18194-24-6 is associated with abnormalities such as Cerebrovascular accident, Renal tubular disorder, Atherosclerosis, Hyperlipoproteinemia Type III and Lipid Metabolism Disorders. The involved functions are known as Process, protein folding, Catalyst, Biochemical Pathway and Fold in Medical Device Material. 18194-24-6 often locates in Tissue membrane, Membrane, periplasm, vesicle membrane and outer membrane. The associated genes with 18194-24-6 are Integral Membrane Proteins, Protein Structure, RTN4 gene, RTN4R gene and Protein, Organized by Structure. The related lipids are Micelles, dimyristoylphosphatidylglycerol, 1,2-dihexadecyl-sn-glycero-3-phosphocholine, Unilamellar Vesicles and cholesteryl oleate. The related experimental models are Mouse Model, Arthritis, Adjuvant-Induced, Disease model and Xenograft Model.

References related to genes published in J. Biol. Chem.

PMID	Journal	Published Date	Author	Title
8798499	J. Biol. Chem.	1996	Raussens V et al.	Hydrogen/deuterium exchange kinetics of apolipophorin-III in lipid-free and phospholipid-bound states. An analysis by Fourier transform infrared spectroscopy.
8995232	J. Biol. Chem.	1997	Riddell DR et al.	Apolipoprotein E inhibits platelet aggregation through the L-arginine:nitric oxide pathway. Implications for vascular disease.
9312118	J. Biol. Chem.	1997	Wang Y et al.	Identification of shallow and deep membrane-penetrating forms of diphtheria toxin T domain that are regulated by protein concentration and bilayer width.
7829491	J. Biol. Chem.	1995	Mishra VK et al.	Effect of the arrangement of tandem repeating units of class A amphipathic alpha-helixes on lipid interaction.
9748256	J. Biol. Chem.	1998	Raussens V et al.	The low density lipoprotein receptor active conformation of apolipoprotein E. Helix organization in n-terminal domain-phospholipid disc particles.
10419496	J. Biol. Chem.	1999	Weers PM et al.	Interaction of an exchangeable apolipoprotein with phospholipid vesicles and lipoprotein particles. Role of leucines 32, 34, and 95 in Locusta migratoria apolipophorin III.
11912196	J. Biol. Chem.	2002	Ji ZS et al.	Apolipoprotein E4 potentiates amyloid beta peptide-induced lysosomal leakage and apoptosis in neuronal cells.
11279152	J. Biol. Chem.	2001	Christensen K et al.	Binding of steroidogenic acute regulatory protein to synthetic membranes suggests an active molten globule.
12393895	J. Biol. Chem.	2002	Morrow JA et al.	Apolipoprotein E4 forms a molten globule. A potential basis for its association with disease.
12670959	J. Biol. Chem.	2003	Zhang W et al.	Binding of peptides with basic and aromatic residues to bilayer membranes: phenylalanine in the myristoylated alanine-rich C kinase substrate effector domain penetrates into the hydrophobic core of the bilayer.
12684504	J. Biol. Chem.	2003	Kiss RS et al.	Structure-guided protein engineering modulates helix bundle exchangeable apolipoprotein properties.
10567370	J. Biol. Chem.	1999	Shen YM et al.	Lipid-dependent activation of protein kinase C-alpha by normal alcohols.
10801877	J. Biol. Chem.	2000	Lu B et al.	Conformational reorganization of the four-helix bundle of human apolipoprotein E in binding to phospholipid.
10751422	J. Biol. Chem.	2000	Klezovitch O et al.	Structural determinants in the C-terminal domain of apolipoprotein E mediating binding to the protein core of human aortic biglycan.
18845546	J. Biol. Chem.	2008	Mishra VK et al.	Effect of leucine to phenylalanine substitution on the nonpolar face of a class A amphipathic helical peptide on its interaction with lipid: high resolution solution NMR studies of 4F-dimyristoylphosphatidylcholine discoidal complex.
17401142	J. Biol. Chem.	2007	Beckstead JA et al.	The C terminus of apolipoprotein A-V modulates lipid-binding activity.
16407255	J. Biol. Chem.	2006	Mishra VK et al.	Association of a model class A (apolipoprotein) amphipathic alpha helical peptide with lipid: high resolution NMR studies of peptide.lipid discoidal complexes.
15485851	J. Biol. Chem.	2004	Bender V et al.	T cell antigen receptor peptide-lipid membrane interactions using surface plasmon resonance.
15878877	J. Biol. Chem.	2005	Lookene A et al.	Apolipoprotein A-V-heparin interactions: implications for plasma lipoprotein metabolism.
16877761	J. Biol. Chem.	2006	Tremouilhac P et al.	Synergistic transmembrane alignment of the antimicrobial heterodimer PGLa/magainin.
16159879	J. Biol. Chem.	2005	Pearson K et al.	Specific sequences in the N and C termini of apolipoprotein A-IV modulate its conformation and lipid association.
23288849	J. Biol. Chem.	2013	Deng X et al.	Small-angle X-ray scattering of apolipoprotein A-IV reveals the importance of its termini for structural stability.
25398882	J. Biol. Chem.	2015	Smrt ST et al.	The influenza hemagglutinin fusion domain is an amphipathic helical hairpin that functions by inducing membrane curvature.