Farnesyl diphosphate

Farnesyl diphosphate is a lipid of Prenol Lipids (PR) class. Farnesyl diphosphate is associated with abnormalities such as Dental caries and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Regulation, Process, Signal, Anabolism and inhibitors. Farnesyl diphosphate often locates in peroxisome, Cytoplasmic matrix, Plasma membrane, soluble and Mitochondria. The associated genes with Farnesyl diphosphate are HSD3B1 gene, ABRA gene, MATN1 gene, SEPSECS gene and MBD2 gene. The related lipids are Sterols, 22-hydroxycholesterol, dehydrosqualene, SK&F 104976 and 25-hydroxycholesterol.

References related to genes published in J. Biol. Chem.

PMID	Journal	Published Date	Author	Title
19386608	J. Biol. Chem.	2009	Yanagida K et al.	Identification and characterization of a novel lysophosphatidic acid receptor, p2y5/LPA6.
8576183	J. Biol. Chem.	1996	Biardi L and Krisans SK	Compartmentalization of cholesterol biosynthesis. Conversion of mevalonate to farnesyl diphosphate occurs in the peroxisomes.
21068379	J. Biol. Chem.	2011	Sasaki D et al.	Crystal structure of heterodimeric hexaprenyl diphosphate synthase from Micrococcus luteus B-P 26 reveals that the small subunit is directly involved in the product chain length regulation.
21693706	J. Biol. Chem.	2011	Nakano C et al.	Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus.
19858213	J. Biol. Chem.	2009	Zhao B et al.	Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site.
21778231	J. Biol. Chem.	2011	Leichner GS et al.	Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein.