N,N-dimethylsphingosine

N,N-dimethylsphingosine is a lipid of Sphingolipids (SP) class. N,n-dimethylsphingosine is associated with abnormalities such as Exanthema and Increased drug resistance. The involved functions are known as Vmax, Metabolic Inhibition, Anabolism, Binding (Molecular Function) and Cytokinesis. N,n-dimethylsphingosine often locates in yolk, Membrane, CNS - Brain (MMHCC), soluble and Tissue membrane. The associated genes with N,N-dimethylsphingosine are FPR1 gene, ANP32A gene, HPGDS gene, Nuclear phosphoprotein and PTGS2 gene. The related lipids are Sphingolipids, Phosphatidic Acid, Lysophosphatidylcholines, stearylamine and dihydroceramide. The related experimental models are Mouse Model and Knock-out.

References related to genes published in J. Biol. Chem.

PMID	Journal	Published Date	Author	Title
9705322	J. Biol. Chem.	1998	Megidish T et al.	A novel sphingosine-dependent protein kinase (SDK1) specifically phosphorylates certain isoforms of 14-3-3 protein.
10747891	J. Biol. Chem.	2000	Cuvillier O et al.	Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells.
10751414	J. Biol. Chem.	2000	Liu H et al.	Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform.
15302883	J. Biol. Chem.	2004	Ibrahim FB et al.	Anaphylatoxin signaling in human neutrophils. A key role for sphingosine kinase.
20558741	J. Biol. Chem.	2010	Habrukowich C et al.	Sphingosine interaction with acidic leucine-rich nuclear phosphoprotein-32A (ANP32A) regulates PP2A activity and cyclooxygenase (COX)-2 expression in human endothelial cells.