Lysophosphatidylcholine

Lysophosphatidylcholine is a lipid of Glycerophospholipids (GP) class. Lysophosphatidylcholine is associated with abnormalities such as Ischemia, Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Fatty Liver and Atherosclerosis. The involved functions are known as Inflammation, antagonists, Signal Transduction, Signal Pathways and Saturated. Lysophosphatidylcholine often locates in Body tissue, Head, integral to membrane, Membrane and Extracellular. The associated genes with Lysophosphatidylcholine are RHOA gene, Homologous Gene, GPR4 gene, GPR68 gene and TRPV2 gene. The related lipids are Nonesterified Fatty Acids, lysophosphatidylethanolamine, Lysophosphatidylcholines, Phosphatidylserines and 25-hydroxycholesterol. The related experimental models are Knock-out and Disease model.

References related to lipids published in J. Biol. Chem.

PMID	Journal	Published Date	Author	Title
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27008858	J. Biol. Chem.	2016	Wong BH et al.	Mfsd2a Is a Transporter for the Essential ω-3 Fatty Acid Docosahexaenoic Acid (DHA) in Eye and Is Important for Photoreceptor Cell Development.
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10318801	J. Biol. Chem.	1999	Ramanadham S et al.	Studies of the role of group VI phospholipase A2 in fatty acid incorporation, phospholipid remodeling, lysophosphatidylcholine generation, and secretagogue-induced arachidonic acid release in pancreatic islets and insulinoma cells.
9774454	J. Biol. Chem.	1998	Biwa T et al.	Induction of murine macrophage growth by oxidized low density lipoprotein is mediated by granulocyte macrophage colony-stimulating factor.
9506985	J. Biol. Chem.	1998	Wong JT et al.	Lysophosphatidylcholine stimulates the release of arachidonic acid in human endothelial cells.
8910311	J. Biol. Chem.	1996	Sakai M et al.	The scavenger receptor serves as a route for internalization of lysophosphatidylcholine in oxidized low density lipoprotein-induced macrophage proliferation.
7542654	J. Biol. Chem.	1995	Zembowicz A et al.	Transcriptional induction of endothelial nitric oxide synthase type III by lysophosphatidylcholine.