phosphatidylinositol-4-phosphate

phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.

References related to lipids published in J. Biol. Chem.


PMIDJournalPublished DateAuthorTitle
26601944J. Biol. Chem.2016Goto A et al.Oxysterol-binding Protein Activation at Endoplasmic Reticulum-Golgi Contact Sites Reorganizes Phosphatidylinositol 4-Phosphate Pools.
24742681J. Biol. Chem.2014Charman M et al.Oxysterol-binding protein (OSBP)-related protein 4 (ORP4) is essential for cell proliferation and survival.
24045945J. Biol. Chem.2013Zhou X et al.Auto-inhibition of Drs2p, a yeast phospholipid flippase, by its carboxyl-terminal tail.
22351780J. Biol. Chem.2012Jacquot A et al.Phosphatidylserine stimulation of Drs2p·Cdc50p lipid translocase dephosphorylation is controlled by phosphatidylinositol-4-phosphate.
10567424J. Biol. Chem.1999Gonzalez-Agosti C et al.Interdomain interaction of merlin isoforms and its influence on intermolecular binding to NHE-RF.
8662856J. Biol. Chem.1996Molz L et al.Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain.