phytosphingosine

phytosphingosine is a lipid of Sphingolipids (SP) class. Phytosphingosine is associated with abnormalities such as Infection, Nodule, Dehydration, Neuropathy and nervous system disorder. The involved functions are known as Saturated, sphingomyelin synthase activity, Heat-Shock Response, Cell Growth and Apoptosis. Phytosphingosine often locates in Clone, Protoplasm, Mitochondria, soluble and Cytoplasmic matrix. The associated genes with phytosphingosine are SGMS1 gene, BCL2 gene, Chromatin, Homologous Gene and DLEU2 gene. The related lipids are Sphingolipids, inositolphosphorylceramide, Phosphatidylserines, dihydroceramide and Fatty Acids. The related experimental models are Knock-out.

References related to lipids published in J. Biol. Chem.

PMID	Journal	Published Date	Author	Title
9446592	J. Biol. Chem.	1998	Skrzypek MS et al.	Inhibition of amino acid transport by sphingoid long chain bases in Saccharomyces cerevisiae.
9092515	J. Biol. Chem.	1997	Nagiec MM et al.	Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene.
11468289	J. Biol. Chem.	2001	Chung N et al.	Phytosphingosine as a specific inhibitor of growth and nutrient import in Saccharomyces cerevisiae.
11877427	J. Biol. Chem.	2002	Bäckhed F et al.	Identification of target tissue glycosphingolipid receptors for uropathogenic, F1C-fimbriated Escherichia coli and its role in mucosal inflammation.
16141212	J. Biol. Chem.	2005	Sano T et al.	Regulation of the sphingoid long-chain base kinase Lcb4p by ergosterol and heme: studies in phytosphingosine-resistant mutants.
22277656	J. Biol. Chem.	2012	Montefusco DJ et al.	Sphingoid bases and the serine catabolic enzyme CHA1 define a novel feedforward/feedback mechanism in the response to serine availability.
11056159	J. Biol. Chem.	2001	Jenkins GM and Hannun YA	Role for de novo sphingoid base biosynthesis in the heat-induced transient cell cycle arrest of Saccharomyces cerevisiae.
21330371	J. Biol. Chem.	2011	Guo L et al.	Phosphatidic acid binds and stimulates Arabidopsis sphingosine kinases.
16129666	J. Biol. Chem.	2005	Mare L et al.	APP1 transcription is regulated by inositol-phosphorylceramide synthase 1-diacylglycerol pathway and is controlled by ATF2 transcription factor in Cryptococcus neoformans.