phosphatidylinositol-4-phosphate

phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.

References related to locations published in J. Biol. Chem.


PMIDJournalPublished DateAuthorTitle
28698382J. Biol. Chem.2017Hirama T et al.Phosphatidylserine dictates the assembly and dynamics of caveolae in the plasma membrane.
24045945J. Biol. Chem.2013Zhou X et al.Auto-inhibition of Drs2p, a yeast phospholipid flippase, by its carboxyl-terminal tail.
22351780J. Biol. Chem.2012Jacquot A et al.Phosphatidylserine stimulation of Drs2p·Cdc50p lipid translocase dephosphorylation is controlled by phosphatidylinositol-4-phosphate.
21300796J. Biol. Chem.2011Shen B et al.Protein targeting to exosomes/microvesicles by plasma membrane anchors.
19095644J. Biol. Chem.2009Brombacher E et al.Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila.
7782308J. Biol. Chem.1995Starling AP et al.Phosphatidylinositol 4-phosphate increases the rate of dephosphorylation of the phosphorylated Ca(2+)-ATPase.