phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

References related to locations published in J. Biol. Chem.

PMID	Journal	Published Date	Author	Title
10066800	J. Biol. Chem.	1999	Klukas O et al.	Localization of two phylloquinones, QK and QK', in an improved electron density map of photosystem I at 4-A resolution.
11489879	J. Biol. Chem.	2001	Boudreaux B et al.	Mutations in both sides of the photosystem I reaction center identify the phylloquinone observed by electron paramagnetic resonance spectroscopy.
12626505	J. Biol. Chem.	2003	Gong XM et al.	Control of electron transport in photosystem I by the iron-sulfur cluster FX in response to intra- and intersubunit interactions.
12721306	J. Biol. Chem.	2003	Xu W et al.	Electron transfer in cyanobacterial photosystem I: II. Determination of forward electron transfer rates of site-directed mutants in a putative electron transfer pathway from A0 through A1 to FX.
10722690	J. Biol. Chem.	2000	Johnson TW et al.	Recruitment of a foreign quinone into the A(1) site of photosystem I. I. Genetic and physiological characterization of phylloquinone biosynthetic pathway mutants in Synechocystis sp. pcc 6803.
10722691	J. Biol. Chem.	2000	Zybailov B et al.	Recruitment of a foreign quinone into the A(1) site of photosystem I. II. Structural and functional characterization of phylloquinone biosynthetic pathway mutants by electron paramagnetic resonance and electron-nuclear double resonance spectroscopy.
21367861	J. Biol. Chem.	2011	Westhofen P et al.	Human vitamin K 2,3-epoxide reductase complex subunit 1-like 1 (VKORC1L1) mediates vitamin K-dependent intracellular antioxidant function.
17339322	J. Biol. Chem.	2007	Lefebvre-Legendre L et al.	Loss of phylloquinone in Chlamydomonas affects plastoquinone pool size and photosystem II synthesis.
18083713	J. Biol. Chem.	2008	Okano T et al.	Conversion of phylloquinone (Vitamin K1) into menaquinone-4 (Vitamin K2) in mice: two possible routes for menaquinone-4 accumulation in cerebra of mice.
17082184	J. Biol. Chem.	2006	Lohmann A et al.	Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.
24085302	J. Biol. Chem.	2013	Hirota Y et al.	Menadione (vitamin K3) is a catabolic product of oral phylloquinone (vitamin K1) in the intestine and a circulating precursor of tissue menaquinone-4 (vitamin K2) in rats.