Sphinganine

Sphinganine is a lipid of Sphingolipids (SP) class. Sphinganine is associated with abnormalities such as Sphingolipidoses, CLEFT LIP, CONGENITAL HEALED, Aortic aneurysm, familial thoracic 4, Morphologically altered structure and Atherosclerosis. The involved functions are known as Transcription, Genetic, Signal, Muscle Contraction, biological adaptation to stress and Gene Expression. Sphinganine often locates in Tissue membrane, Membrane, Protoplasm, Plasma membrane and Cytoplasmic. The associated genes with Sphinganine are SLC33A1 gene, HM13 gene, P4HTM gene, SPHK1 gene and SPHK2 gene. The related lipids are Sphingolipids, Phosphatidylserines, Sterols, Fatty Acids and inositolphosphorylceramide. The related experimental models are Mouse Model and Knock-out.

References related to locations published in J. Biol. Chem.

PMID	Journal	Published Date	Author	Title
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19648650	J. Biol. Chem.	2009	Hornemann T et al.	The SPTLC3 subunit of serine palmitoyltransferase generates short chain sphingoid bases.
17322298	J. Biol. Chem.	2007	Cowart LA and Hannun YA	Selective substrate supply in the regulation of yeast de novo sphingolipid synthesis.
15328338	J. Biol. Chem.	2004	Kihara A and Igarashi Y	FVT-1 is a mammalian 3-ketodihydrosphingosine reductase with an active site that faces the cytosolic side of the endoplasmic reticulum membrane.