phytosphingosine

phytosphingosine is a lipid of Sphingolipids (SP) class. Phytosphingosine is associated with abnormalities such as Infection, Nodule, Dehydration, Neuropathy and nervous system disorder. The involved functions are known as Saturated, sphingomyelin synthase activity, Heat-Shock Response, Cell Growth and Apoptosis. Phytosphingosine often locates in Clone, Protoplasm, Mitochondria, soluble and Cytoplasmic matrix. The associated genes with phytosphingosine are SGMS1 gene, BCL2 gene, Chromatin, Homologous Gene and DLEU2 gene. The related lipids are Sphingolipids, inositolphosphorylceramide, Phosphatidylserines, dihydroceramide and Fatty Acids. The related experimental models are Knock-out.

References related to locations published in J. Biol. Chem.

PMID	Journal	Published Date	Author	Title
11877427	J. Biol. Chem.	2002	Bäckhed F et al.	Identification of target tissue glycosphingolipid receptors for uropathogenic, F1C-fimbriated Escherichia coli and its role in mucosal inflammation.
10764732	J. Biol. Chem.	2000	Chung N et al.	Sphingolipids signal heat stress-induced ubiquitin-dependent proteolysis.
14522966	J. Biol. Chem.	2003	Park MT et al.	Suppression of extracellular signal-related kinase and activation of p38 MAPK are two critical events leading to caspase-8- and mitochondria-mediated cell death in phytosphingosine-treated human cancer cells.
16141212	J. Biol. Chem.	2005	Sano T et al.	Regulation of the sphingoid long-chain base kinase Lcb4p by ergosterol and heme: studies in phytosphingosine-resistant mutants.