N-Palmitoylsphingosine is a lipid of Sphingolipids (SP) class. The involved functions are known as ceramide biosynthetic process, Apoptosis, Regulation, Signal Transduction and Caspase-Dependent Apoptosis. N-palmitoylsphingosine often locates in Mitochondria, Membrane, Extracellular and Endoplasmic Reticulum. The associated genes with N-Palmitoylsphingosine are BCL2 gene, cytochrome c'', BCL2L1 gene, LASS6 gene and LASS5 gene. The related lipids are dihydroceramide, Fatty Acids, Sphingolipids, Palmitates and inositolphosphorylceramide.
PMID | Journal | Published Date | Author | Title |
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12006562 | J. Biol. Chem. | 2002 | Siskind LJ et al. | Ceramide channels increase the permeability of the mitochondrial outer membrane to small proteins. |
11027675 | J. Biol. Chem. | 2000 | Siskind LJ and Colombini M | The lipids C2- and C16-ceramide form large stable channels. Implications for apoptosis. |