Cholic acid
Cholic acid is a lipid of Sterol Lipids (ST) class. Cholic acid is associated with abnormalities such as Cholestasis, Intrahepatic Cholestasis, Atherosclerosis, Diabetes and cholesterol gallstones. The involved functions are known as Homeostasis, Enterohepatic Circulation, Proliferation (morphologic abnormality), Process and Cell Proliferation. Cholic acid often locates in Hepatic, Cytoplasmic matrix, Membrane, Protoplasm and Tissue membrane. The associated genes with Cholic acid are CYP27A1 gene, ABCB11 gene, NR5A2 gene, SLC10A2 gene and SLC10A1 gene. The related lipids are ursocholic acid, Steroids, Cholestenes, Cholestanes and cholanic acid.
References related to locations published in J. Biol. Chem.
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 10749848 | J. Biol. Chem. | 2000 | Steinberg SJ et al. | The human liver-specific homolog of very long-chain acyl-CoA synthetase is cholate:CoA ligase. |
| 11980911 | J. Biol. Chem. | 2002 | Mihalik SJ et al. | Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling. |
| 18842595 | J. Biol. Chem. | 2008 | Fang S et al. | The p300 acetylase is critical for ligand-activated farnesoid X receptor (FXR) induction of SHP. |
| 20233723 | J. Biol. Chem. | 2010 | Schmidt DR et al. | Regulation of bile acid synthesis by fat-soluble vitamins A and D. |
| 21680746 | J. Biol. Chem. | 2011 | Liaset B et al. | Nutritional regulation of bile acid metabolism is associated with improved pathological characteristics of the metabolic syndrome. |
| 19458090 | J. Biol. Chem. | 2009 | Vankemmelbeke M et al. | Energy-dependent immunity protein release during tol-dependent nuclease colicin translocation. |